Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50001943
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50450837(CHEMBL397985 | 8-pCPT-2''-O-Me-cAMP)
Affinity DataEC50:  2.20E+3nMAssay Description:Activation of EPAC1 DEP1 deletion mutant (unknown origin) expressed in mouse NIH-3T3-A14 cells assessed as increase in Rap1b- fluorescent nucleotide ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 4(Mouse)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50098793(CHEMBL3593342)
Affinity DataIC50: 900nMAssay Description:Displacement of 8-NBD-cAMP from mouse EPAC2 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 4(Mouse)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50098719(CHEMBL3593329)
Affinity DataIC50: 1.90E+3nMAssay Description:Displacement of 8-NBD-cAMP from mouse EPAC2 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50098793(CHEMBL3593342)
Affinity DataIC50: 2.40E+3nMAssay Description:Displacement of 8-NBD-cAMP from recombinant human EPAC1 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50098719(CHEMBL3593329)
Affinity DataIC50: 2.40E+3nMAssay Description:Displacement of 8-NBD-cAMP from recombinant human EPAC1 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50011360(CHEMBL3260990)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of EPAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 4(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50011360(CHEMBL3260990)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of EPAC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 4(Mouse)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50098730(CHEMBL3594316)
Affinity DataIC50: 5.98E+4nMAssay Description:Displacement of 8-NBD-cAMP from mouse EPAC2 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed