41 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
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Article Title
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Discovery of small molecule integrin alphavbeta3 antagonists as novel anticancer agents.
University of Southern California
Synthesis and biological evaluation of dimeric RGD peptide-paclitaxel conjugate as a model for integrin-targeted drug delivery.
University of Southern California
Application of CoMFA and CoMSIA 3D-QSAR and docking studies in optimization of mercaptobenzenesulfonamides as HIV-1 integrase inhibitors.
University of Southern California
Small molecule inhibitors of signal transducer and activator of transcription 3 (Stat3) protein.
University of Southern California
Discovery of a novel series of inhibitors of lymphoid tyrosine phosphatase with activity in human T cells.
University of Southern California
Synthesis, chiral high performance liquid chromatographic resolution and enantiospecific activity of a potent new geranylgeranyl transferase inhibitor, 2-hydroxy-3-imidazo[1,2-a]pyridin-3-yl-2-phosphonopropionic acid.
University of Southern California
Farnesyl pyrophosphate synthase enantiospecificity with a chiral risedronate analog, [6,7-dihydro-5H-cyclopenta[c]pyridin-7-yl(hydroxy)methylene]bis(phosphonic acid) (NE-10501): Synthetic, structural, and modeling studies.
University of Southern California
Design, synthesis, and estrogenic activity of a novel estrogen receptor modulator--a hybrid structure of 17beta-estradiol and vitamin E in hippocampal neurons.
University of Southern California
Structure-based virtual screening for plant-based ERbeta-selective ligands as potential preventative therapy against age-related neurodegenerative diseases.
University of Southern California
Discovery of novel small-molecule inhibitors of human epidermal growth factor receptor-2: combined ligand and target-based approach.
University of Southern California
A highly efficient route to enantiomerically pure l-N-Bz-Pmp(t-Bu)2-OH and incorporation into a peptide-based protein tyrosine phosphatase inhibitor.
University of Southern California
Synthesis and biological evaluation of alpha-halogenated bisphosphonate and phosphonocarboxylate analogues of risedronate.
University of Southern California
Design, synthesis, and biological activity of dual monoamine oxidase A and heat shock protein 90 inhibitors, N-Methylpropargylamine-conjugated 4-isopropylresorcinol for glioblastoma.
University of Southern California
Alkyne as a Latent Warhead to Covalently Target SARS-CoV-2 Main Protease.
University of Southern California
Synthesis and anti-cancer potential of potent peripheral MAOA inhibitors designed to limit blood:brain penetration.
University of Southern California
Inhibition of HIV-1 integrase activity by synthetic peptides derived from the HIV-1 HXB2 Pol region of the viral genome.
University of Southern California
-Methylpropargylamine-Conjugated Hydroxamic Acids as Dual Inhibitors of Monoamine Oxidase A and Histone Deacetylase for Glioma Treatment.
University of Southern California
Diketo acid pharmacophore. 2. Discovery of structurally diverse inhibitors of HIV-1 integrase.
University of Southern California
GPCR Agonist-to-Antagonist Conversion: Enabling the Design of Nucleoside Functional Switches for the A
University of Southern California
Beta-diketo acid pharmacophore hypothesis. 1. Discovery of a novel class of HIV-1 integrase inhibitors.
University of Southern California
Inhibition of lysosomal cysteine proteases by chrysotherapeutic compounds: a possible mechanism for the antiarthritic activity of Au(I).
University of Southern California
Development of a Potent and Specific FGFR4 Inhibitor for the Treatment of Hepatocellular Carcinoma.
University of Southern California
Rigidification Dramatically Improves Inhibitor Selectivity for RAF Kinases.
University of Southern California
Development of Alkyne-Containing Pyrazolopyrimidines To Overcome Drug Resistance of Bcr-Abl Kinase.
University of Southern California
Discovery of a novel 5-carbonyl-1H-imidazole-4-carboxamide class of inhibitors of the HIV-1 integrase-LEDGF/p75 interaction.
University of Southern California
Fragment-based discovery of 8-hydroxyquinoline inhibitors of the HIV-1 integrase-lens epithelium-derived growth factor/p75 (IN-LEDGF/p75) interaction.
University of Southern California
Discovery of novel inhibitors of LEDGF/p75-IN protein-protein interactions.
University of Southern California
Development of the next generation of HIV-1 integrase inhibitors: pyrazolone as a novel inhibitor scaffold.
University of Southern California
Discovery of 3-acetyl-4-hydroxy-2-pyranone derivatives and their difluoridoborate complexes as a novel class of HIV-1 integrase inhibitors.
University of Southern California
Quinolone 3-carboxylic acid pharmacophore: design of second generation HIV-1 integrase inhibitors.
University of Southern California
Discovery of novel non-cytotoxic salicylhydrazide containing HIV-1 integrase inhibitors.
University of Southern California
Discovery of structurally diverse HIV-1 integrase inhibitors based on a chalcone pharmacophore.
University of Southern California
Substituted 2-pyrrolinone inhibitors of HIV-1 integrase.
University of Southern California
Effects of rigidity on the selectivity of protein kinase inhibitors.
University of Southern California
In-cell production of a genetically-encoded library based on the θ-defensin RTD-1 using a bacterial expression system.
University of Southern California
Cyclotides, a versatile ultrastable micro-protein scaffold for biotechnological applications.
University of Southern California
Structure-Based Discovery of New Antagonist and Biased Agonist Chemotypes for the Kappa Opioid Receptor.
University of Southern California
