Compile Data Set for Download or QSAR
Report error Found 47 Enz. Inhib. hit(s) with all data for entry = 50012724
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50121972(Compound 3 | CHEMBL157373)
Affinity DataEC50:  1.78E+4nMAssay Description:Effective concentration of the compound against viral replication by Reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50121971(2-Mercapto-benzoic acid N'-(2-mercapto-benzoyl)-hy...)
Affinity DataEC50:  4.30E+3nMAssay Description:Effective concentration of the compound against viral replication by Reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50121970(11,12,13,14,25,26,27,28-octahydrotetrabenzo[c,i,m,...)
Affinity DataEC50:  6.00E+3nMAssay Description:Effective concentration of the compound against viral replication by Reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50056891(CHEMBL36303 | cid_65303 | 2-Hydroxy-benzoic acid N...)
Affinity DataIC50: 700nMAssay Description:Inhibitory activity against HIV-1 integrase (pre-incubated with Mn+2, and drug for 30 min followed by DNA for 1h) in strand transfer of preassembleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50056891(CHEMBL36303 | cid_65303 | 2-Hydroxy-benzoic acid N...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory activity against HIV-1 integrase (pre-incubated with Mn+2, and drug for 30 min followed by DNA for 1h) in 3''-processing of preassembleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50121970(11,12,13,14,25,26,27,28-octahydrotetrabenzo[c,i,m,...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibitory activity against HIV-1 integrase (pre-incubated with Mn+2, and drug for 30 min followed by DNA for 1h) in 3''-processing of preassembleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50121972(Compound 3 | CHEMBL157373)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibitory activity against HIV-1 integrase (pre-incubated with Mn+2, and drug for 30 min followed by DNA for 1h) in 3''-processing of preassembleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50121972(Compound 3 | CHEMBL157373)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibitory activity against HIV-1 integrase (pre-incubated with Mn+2, and drug for 30 min followed by DNA for 1h) in strand transfer of preassembleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50121971(2-Mercapto-benzoic acid N'-(2-mercapto-benzoyl)-hy...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity against HIV-1 integrase (pre-incubated with Mn+2, and drug for 30 min followed by DNA for 1h) in strand transfer of preassembleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50121970(11,12,13,14,25,26,27,28-octahydrotetrabenzo[c,i,m,...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity against HIV-1 integrase (pre-incubated with Mn+2, and DNA on ice for 15 min followed by drug for 1h) in 3'' processing of postass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50121970(11,12,13,14,25,26,27,28-octahydrotetrabenzo[c,i,m,...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity against HIV-1 integrase (pre-incubated with Mn+2, and DNA on ice for 15 min followed by drug for 1h) in strand transfer of postas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50121970(11,12,13,14,25,26,27,28-octahydrotetrabenzo[c,i,m,...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity against HIV-1 integrase (pre-incubated with Mg+2, and DNA on ice for 15 min followed by drug for 1h) in strand transfer of postas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50121971(2-Mercapto-benzoic acid N'-(2-mercapto-benzoyl)-hy...)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibitory activity against HIV-1 integrase (pre-incubated with Mn+2, and drug for 30 min followed by DNA for 1h) in 3''-processing of preassembleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50121970(11,12,13,14,25,26,27,28-octahydrotetrabenzo[c,i,m,...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibitory activity against HIV-1 integrase (pre-incubated with Mg+2, and DNA on ice for 15 min followed by drug for 1h) in 3'' processing of postass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50121970(11,12,13,14,25,26,27,28-octahydrotetrabenzo[c,i,m,...)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibitory activity against HIV-1 integrase (pre-incubated with Mn+2, and drug for 30 min followed by DNA for 1h) in strand transfer of preassembleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50121972(Compound 3 | CHEMBL157373)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibitory activity against HIV-1 integrase (pre-incubated with Mn+2, and DNA on ice for 15 min followed by drug for 1h) in 3'' processing of postass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50121972(Compound 3 | CHEMBL157373)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibitory activity against HIV-1 integrase (pre-incubated with Mn+2, and DNA on ice for 15 min followed by drug for 1h) in strand transfer of postas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50056891(CHEMBL36303 | cid_65303 | 2-Hydroxy-benzoic acid N...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against HIV-1 integrase (pre-incubated with Mn+2, and DNA on ice for 15 min followed by drug for 1h) in strand transfer of postas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50121970(11,12,13,14,25,26,27,28-octahydrotetrabenzo[c,i,m,...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibitory activity against HIV-1 integrase (pre-incubated with Mg+2, and drug for 30 min followed by DNA for 1h) in strand transfer of preassembleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50121970(11,12,13,14,25,26,27,28-octahydrotetrabenzo[c,i,m,...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibitory activity against HIV-1 integrase (preincubated with Mg+2, and drug for 30 min followed by DNA for 1h) in 3''-processing of preassembleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50121971(2-Mercapto-benzoic acid N'-(2-mercapto-benzoyl)-hy...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibitory activity against HIV-1 integrase (pre-incubated with Mg+2, and drug for 30 min followed by DNA for 1h) in strand transfer of preassembleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50121972(Compound 3 | CHEMBL157373)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibitory activity against HIV-1 integrase (pre-incubated with Mg+2, and drug for 30 min followed by DNA for 1h) in strand transfer of preassembleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50121971(2-Mercapto-benzoic acid N'-(2-mercapto-benzoyl)-hy...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibitory activity against HIV-1 integrase (pre-incubated with Mn+2, and DNA on ice for 15 min followed by drug for 1h) in strand transfer of postas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50056891(CHEMBL36303 | cid_65303 | 2-Hydroxy-benzoic acid N...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibitory activity against HIV-1 integrase (pre-incubated with Mn+2, and DNA on ice for 15 min followed by drug for 1h) in 3'' processing of postass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50121972(Compound 3 | CHEMBL157373)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibitory activity against HIV-1 integrase (preincubated with Mg+2, and drug for 30 min followed by DNA for 1h) in 3''-processing of preassembleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50121972(Compound 3 | CHEMBL157373)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibitory activity against HIV-1 integrase (pre-incubated with Mg+2, and DNA on ice for 15 min followed by drug for 1h) in strand transfer of postas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50121971(2-Mercapto-benzoic acid N'-(2-mercapto-benzoyl)-hy...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibitory activity against HIV-1 integrase (pre-incubated with Mg+2, and DNA on ice for 15 min followed by drug for 1h) in strand transfer of postas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50121971(2-Mercapto-benzoic acid N'-(2-mercapto-benzoyl)-hy...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory activity against HIV-1 integrase (pre-incubated with Mg+2, and DNA on ice for 15 min followed by drug for 1h) in 3'' processing of postass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50121971(2-Mercapto-benzoic acid N'-(2-mercapto-benzoyl)-hy...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory activity against HIV-1 integrase (preincubated with Mg+2, and drug for 30 min followed by DNA for 1h) in 3''-processing of preassembleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50121972(Compound 3 | CHEMBL157373)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory activity against HIV-1 integrase (pre-incubated with Mg+2, and DNA on ice for 15 min followed by drug for 1h) in 3'' processing of postass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50121971(2-Mercapto-benzoic acid N'-(2-mercapto-benzoyl)-hy...)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibitory activity against HIV-1 integrase (pre-incubated with Mn+2, and DNA on ice for 15 min followed by drug for 1h) in 3'' processing of postass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50121971(2-Mercapto-benzoic acid N'-(2-mercapto-benzoyl)-hy...)
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibitory activity against viral proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50121970(11,12,13,14,25,26,27,28-octahydrotetrabenzo[c,i,m,...)
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibitory activity against viral proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50121972(Compound 3 | CHEMBL157373)
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibitory activity against viral proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50121970(11,12,13,14,25,26,27,28-octahydrotetrabenzo[c,i,m,...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against viral proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50121971(2-Mercapto-benzoic acid N'-(2-mercapto-benzoyl)-hy...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against viral attachmentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50121972(Compound 3 | CHEMBL157373)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against viral attachmentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50121970(11,12,13,14,25,26,27,28-octahydrotetrabenzo[c,i,m,...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against RAdT of HIV-1 Reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50121972(Compound 3 | CHEMBL157373)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against RAdT of HIV-1 Reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50121971(2-Mercapto-benzoic acid N'-(2-mercapto-benzoyl)-hy...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against rCdG of HIV-1 Reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50121972(Compound 3 | CHEMBL157373)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against rCdG of HIV-1 Reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50121970(11,12,13,14,25,26,27,28-octahydrotetrabenzo[c,i,m,...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against rCdG of HIV-1 Reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50121971(2-Mercapto-benzoic acid N'-(2-mercapto-benzoyl)-hy...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against RAdT of HIV-1 Reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50056891(CHEMBL36303 | cid_65303 | 2-Hydroxy-benzoic acid N...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibitory activity against HIV-1 integrase (pre-incubated with Mg+2, and DNA on ice for 15 min followed by drug for 1h) in 3'' processing of postass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50056891(CHEMBL36303 | cid_65303 | 2-Hydroxy-benzoic acid N...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibitory activity against HIV-1 integrase (pre-incubated with Mg+2, and DNA on ice for 15 min followed by drug for 1h) in strand transfer of postas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50056891(CHEMBL36303 | cid_65303 | 2-Hydroxy-benzoic acid N...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibitory activity against HIV-1 integrase (pre-incubated with Mg+2, and drug for 30 min followed by DNA for 1h) in strand transfer of preassembleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50056891(CHEMBL36303 | cid_65303 | 2-Hydroxy-benzoic acid N...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibitory activity against HIV-1 integrase (preincubated with Mg+2, and drug for 30 min followed by DNA for 1h) in 3''-processing of preassembleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed