Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50039150
TargetFarnesyl pyrophosphate synthase(Human)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM25308((1-hydroxy-2-{imidazo[1,2-a]pyridin-3-yl}-1-phosph...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human FPPS after 10 mins using [14C]IPP as substrate by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM25308((1-hydroxy-2-{imidazo[1,2-a]pyridin-3-yl}-1-phosph...)
Affinity DataIC50: 670nMAssay Description:Inhibition of GGPPS after 10 mins using [14C]IPP as substrate by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50318032(CHEMBL1099309 | (+)-2-hydroxy-3-imidazo[1,2-a]pyri...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human FPPS after 10 mins using [14C]IPP as substrate by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50318032(CHEMBL1099309 | (+)-2-hydroxy-3-imidazo[1,2-a]pyri...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of GGPPS after 10 mins using [14C]IPP as substrate by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50318032(CHEMBL1099309 | (+)-2-hydroxy-3-imidazo[1,2-a]pyri...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of GGPPS after 10 mins using [14C]IPP as substrate by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50226002((R)-2-hydroxy-2-phosphono-3-(pyridin-3-yl)propanoi...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human FPPS after 10 mins using [14C]IPP as substrate by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed