24 articles for thisTarget
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Synthesis and SAR studies of 2-oxoquinoline derivatives as CB2 receptor inverse agonists.

University of Kuopio
Synthesis and CB1 receptor activities of novel arachidonyl alcohol derivatives.

University of Kuopio
N-(3-(4-Hydroxyphenyl)-propenoyl)-amino acid tryptamides as SIRT2 inhibitors.

University of Kuopio
N,N'-Bisbenzylidenebenzene-1,4-diamines and N,N'-Bisbenzylidenenaphthalene-1,4-diamines as Sirtuin Type 2 (SIRT2) Inhibitors.

University of Kuopio
Quantitative structure-activity relationship analysis of inhibitors of the nicotine metabolizing CYP2A6 enzyme.

University of Kuopio
Dicarboxylic acid azacycle l-prolyl-pyrrolidine amides as prolyl oligopeptidase inhibitors and three-dimensional quantitative structure-activity relationship of the enzyme-inhibitor interactions.

University of Kuopio
Predictive three-dimensional quantitative structure-activity relationship of cytochrome P450 1A2 inhibitors.

University of Kuopio
Molecular determinants of steroid inhibition for the mouse constitutive androstane receptor.

University of Kuopio
The synthesis and biological evaluation of para-substituted phenolic N-alkyl carbamates as endocannabinoid hydrolyzing enzyme inhibitors.

University of Kuopio
Glucose promoiety enables glucose transporter mediated brain uptake of ketoprofen and indomethacin prodrugs in rats.

University of Kuopio
N(epsilon)-thioacetyl-lysine-containing tri-, tetra-, and pentapeptides as SIRT1 and SIRT2 inhibitors.

University of Kuopio
Characterization of the binding properties of SIRT2 inhibitors with a N-(3-phenylpropenoyl)-glycine tryptamide backbone.

University of Kuopio
Oxadiazole-carbonylaminothioureas as SIRT1 and SIRT2 inhibitors.

University of Kuopio
Discovering inhibitors of human sirtuin type 2: novel structural scaffolds.

University of Kuopio
Fatty acid amide hydrolase inhibitors from virtual screening of the endocannabinoid system.

University of Kuopio
Synthesis and characterization of the novel fluorescent prolyl oligopeptidase inhibitor 4-fluoresceinthiocarbamoyl-6-aminocaproyl-L-prolyl-2(S)-(hydroxyacetyl)pyrrolidine.

University of Kuopio
An in silico approach to discovering novel inhibitors of human sirtuin type 2.

University of Kuopio
A cyclopent-2-enecarbonyl group mimics proline at the P2 position of prolyl oligopeptidase inhibitors.

University of Kuopio
New prolyl oligopeptidase inhibitors developed from dicarboxylic acid bis(l-prolyl-pyrrolidine) amides.

University of Kuopio
Dicarboxylic acid bis(L-prolyl-pyrrolidine) amides as prolyl oligopeptidase inhibitors.

University of Kuopio
Virtual screening of novel CB2 ligands using a comparative model of the human cannabinoid CB2 receptor.

University of Kuopio
Alpha-methylated derivatives of 2-arachidonoyl glycerol: synthesis, CB1 receptor activity, and enzymatic stability.

University of Kuopio
3D-QSAR studies on cannabinoid CB1 receptor agonists: G-protein activation as biological data.

University of Kuopio
Synthesis and in vitro pharmacology of a series of new chiral histamine H3-receptor ligands: 2-(R and S)-Amino-3-(1H-imidazol-4(5)-yl)propyl ether derivatives.

University of Kuopio