Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 50028472
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257407(His-Lys-Lys(epsilon-thioAc)Ala-Met | CHEMBL504310)
Affinity DataIC50: 180nMAssay Description:Inhibition of recombinant SIRT1 preincubated for 5 mins before addition of substrate measured after 1 hr by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257289(Ser-Lys-Lys(epsilon-thioAc)Thr-Ile | CHEMBL505399)
Affinity DataIC50: 180nMAssay Description:Inhibition of recombinant SIRT1 preincubated for 5 mins before addition of substrate measured after 1 hr by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257348(Ser-Ala-Lys(epsilon-thioAc)Thr-Ile | CHEMBL492925)
Affinity DataIC50: 220nMAssay Description:Inhibition of recombinant SIRT1 preincubated for 5 mins before addition of substrate measured after 1 hr by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257345(His-Lys-Lys(epsilon-thioAc)Thr-Ile | CHEMBL510904)
Affinity DataIC50: 230nMAssay Description:Inhibition of recombinant SIRT1 preincubated for 5 mins before addition of substrate measured after 1 hr by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50178769(6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...)
Affinity DataIC50: 280nMAssay Description:Inhibition of recombinant SIRT1 preincubated for 5 mins before addition of substrate measured after 1 hr by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257239(His-Lys-Lys(epsilon-thioAc)-Leu-Met | CHEMBL447677)
Affinity DataIC50: 330nMAssay Description:Inhibition of recombinant SIRT1 preincubated for 5 mins before addition of substrate measured after 1 hr by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257286(Lys-Lys(epsilon-thioAc)-Leu-Met | CHEMBL521807)
Affinity DataIC50: 330nMAssay Description:Inhibition of recombinant SIRT1 preincubated for 5 mins before addition of substrate measured after 1 hr by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257405(Ala-Lys-Lys(epsilon-thioAc)Leu-Met | CHEMBL504711)
Affinity DataIC50: 380nMAssay Description:Inhibition of recombinant SIRT1 preincubated for 5 mins before addition of substrate measured after 1 hr by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257285(His-Lys-Lys(epsilon-thioAc)-Leu | CHEMBL492308)
Affinity DataIC50: 480nMAssay Description:Inhibition of recombinant SIRT1 preincubated for 5 mins before addition of substrate measured after 1 hr by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257406(His-Ala-Lys(epsilon-thioAc)Leu-Met | CHEMBL453807)
Affinity DataIC50: 550nMAssay Description:Inhibition of recombinant SIRT1 preincubated for 5 mins before addition of substrate measured after 1 hr by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257287(Lys-Lys(epsilon-thioAc)-Leu | CHEMBL492309)
Affinity DataIC50: 570nMAssay Description:Inhibition of recombinant SIRT1 preincubated for 5 mins before addition of substrate measured after 1 hr by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257408(His-Lys-Lys(epsilon-thioAc)Leu-Ala | CHEMBL449883)
Affinity DataIC50: 900nMAssay Description:Inhibition of recombinant SIRT1 preincubated for 5 mins before addition of substrate measured after 1 hr by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257291(Ser-Asp-Lys(epsilon-thioAc)Thr-Met | CHEMBL492710)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of recombinant SIRT1 preincubated for 5 mins before addition of substrate measured after 1 hr by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257347(Ala-Asp-Lys(epsilon-thioAc)Thr-Ile | CHEMBL523676)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of recombinant SIRT1 preincubated for 5 mins before addition of substrate measured after 1 hr by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257407(His-Lys-Lys(epsilon-thioAc)Ala-Met | CHEMBL504310)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of recombinant SIRT2 preincubated for 5 mins before addition of substrate measured after 3 hrs by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257288(His-Asp-Lys(epsilon-thioAc)Thr-Ile | CHEMBL452893)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of recombinant SIRT1 preincubated for 5 mins before addition of substrate measured after 1 hr by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257237(Asp-Lys(epsilon-thioAc)-Thr-Ile | CHEMBL493160)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of recombinant SIRT1 preincubated for 5 mins before addition of substrate measured after 1 hr by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257200(Ser-Asp-Lys(epsilon-thioAc)-Thr-Ile | CHEMBL507676)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant SIRT1 preincubated for 5 mins before addition of substrate measured after 1 hr by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257348(Ser-Ala-Lys(epsilon-thioAc)Thr-Ile | CHEMBL492925)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of recombinant SIRT2 preincubated for 5 mins before addition of substrate measured after 3 hrs by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257239(His-Lys-Lys(epsilon-thioAc)-Leu-Met | CHEMBL447677)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of recombinant SIRT2 preincubated for 5 mins before addition of substrate measured after 3 hrs by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257349(Ser-Asp-Lys(epsilon-thioAc)Ala-Ile | CHEMBL523498)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of recombinant SIRT1 preincubated for 5 mins before addition of substrate measured after 1 hr by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257289(Ser-Lys-Lys(epsilon-thioAc)Thr-Ile | CHEMBL505399)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of recombinant SIRT2 preincubated for 5 mins before addition of substrate measured after 3 hrs by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257345(His-Lys-Lys(epsilon-thioAc)Thr-Ile | CHEMBL510904)
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of recombinant SIRT2 preincubated for 5 mins before addition of substrate measured after 3 hrs by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257405(Ala-Lys-Lys(epsilon-thioAc)Leu-Met | CHEMBL504711)
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of recombinant SIRT2 preincubated for 5 mins before addition of substrate measured after 3 hrs by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257404(Ser-Asp-Lys(epsilon-thioAc)Thr-Ala | CHEMBL492521)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of recombinant SIRT1 preincubated for 5 mins before addition of substrate measured after 1 hr by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257239(His-Lys-Lys(epsilon-thioAc)-Leu-Met | CHEMBL447677)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GST-tagged SIRT2 expressed in Escherichia coli after 60 mins by Dixon plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257239(His-Lys-Lys(epsilon-thioAc)-Leu-Met | CHEMBL447677)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GST-tagged SIRT1 expressed in Escherichia coli after 10 mins by Dixon plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257291(Ser-Asp-Lys(epsilon-thioAc)Thr-Met | CHEMBL492710)
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of recombinant SIRT2 preincubated for 5 mins before addition of substrate measured after 3 hrs by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257346(Ser-Asp-Lys(epsilon-thioAc)Leu-Met | CHEMBL447852)
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibition of recombinant SIRT1 preincubated for 5 mins before addition of substrate measured after 1 hr by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257236(Ser-Asp-Lys(epsilon-thioAc)-Thr | CHEMBL493159)
Affinity DataIC50: 1.11E+4nMAssay Description:Inhibition of recombinant SIRT1 preincubated for 5 mins before addition of substrate measured after 1 hr by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257238(Asp-Lys(epsilon-thioAc)-Thr | CHEMBL493355)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of recombinant SIRT1 preincubated for 5 mins before addition of substrate measured after 1 hr by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50178769(6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of recombinant SIRT2 preincubated for 5 mins before addition of substrate measured after 3 hrs by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257406(His-Ala-Lys(epsilon-thioAc)Leu-Met | CHEMBL453807)
Affinity DataIC50: 1.65E+4nMAssay Description:Inhibition of recombinant SIRT2 preincubated for 5 mins before addition of substrate measured after 3 hrs by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257285(His-Lys-Lys(epsilon-thioAc)-Leu | CHEMBL492308)
Affinity DataIC50: 1.99E+4nMAssay Description:Inhibition of recombinant SIRT2 preincubated for 5 mins before addition of substrate measured after 3 hrs by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257290(Ser-Asp-Lys(epsilon-thioAc)Leu-Ile | CHEMBL503595)
Affinity DataIC50: 2.32E+4nMAssay Description:Inhibition of recombinant SIRT1 preincubated for 5 mins before addition of substrate measured after 1 hr by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257200(Ser-Asp-Lys(epsilon-thioAc)-Thr-Ile | CHEMBL507676)
Affinity DataIC50: 2.91E+4nMAssay Description:Inhibition of recombinant SIRT2 preincubated for 5 mins before addition of substrate measured after 3 hrs by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257288(His-Asp-Lys(epsilon-thioAc)Thr-Ile | CHEMBL452893)
Affinity DataIC50: 3.11E+4nMAssay Description:Inhibition of recombinant SIRT2 preincubated for 5 mins before addition of substrate measured after 3 hrs by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257408(His-Lys-Lys(epsilon-thioAc)Leu-Ala | CHEMBL449883)
Affinity DataIC50: 3.33E+4nMAssay Description:Inhibition of recombinant SIRT2 preincubated for 5 mins before addition of substrate measured after 3 hrs by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257347(Ala-Asp-Lys(epsilon-thioAc)Thr-Ile | CHEMBL523676)
Affinity DataIC50: 3.74E+4nMAssay Description:Inhibition of recombinant SIRT2 preincubated for 5 mins before addition of substrate measured after 3 hrs by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257236(Ser-Asp-Lys(epsilon-thioAc)-Thr | CHEMBL493159)
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of recombinant SIRT2 preincubated for 5 mins before addition of substrate measured after 3 hrs by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257286(Lys-Lys(epsilon-thioAc)-Leu-Met | CHEMBL521807)
Affinity DataIC50: 4.98E+4nMAssay Description:Inhibition of recombinant SIRT2 preincubated for 5 mins before addition of substrate measured after 3 hrs by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257349(Ser-Asp-Lys(epsilon-thioAc)Ala-Ile | CHEMBL523498)
Affinity DataIC50: 7.28E+4nMAssay Description:Inhibition of recombinant SIRT2 preincubated for 5 mins before addition of substrate measured after 3 hrs by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257237(Asp-Lys(epsilon-thioAc)-Thr-Ile | CHEMBL493160)
Affinity DataIC50: 8.34E+4nMAssay Description:Inhibition of recombinant SIRT2 preincubated for 5 mins before addition of substrate measured after 3 hrs by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257404(Ser-Asp-Lys(epsilon-thioAc)Thr-Ala | CHEMBL492521)
Affinity DataIC50: 8.46E+4nMAssay Description:Inhibition of recombinant SIRT2 preincubated for 5 mins before addition of substrate measured after 3 hrs by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257346(Ser-Asp-Lys(epsilon-thioAc)Leu-Met | CHEMBL447852)
Affinity DataIC50: 9.29E+4nMAssay Description:Inhibition of recombinant SIRT2 preincubated for 5 mins before addition of substrate measured after 3 hrs by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257287(Lys-Lys(epsilon-thioAc)-Leu | CHEMBL492309)
Affinity DataIC50: 1.51E+5nMAssay Description:Inhibition of recombinant SIRT2 preincubated for 5 mins before addition of substrate measured after 3 hrs by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257238(Asp-Lys(epsilon-thioAc)-Thr | CHEMBL493355)
Affinity DataIC50: 1.75E+5nMAssay Description:Inhibition of recombinant SIRT2 preincubated for 5 mins before addition of substrate measured after 3 hrs by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257290(Ser-Asp-Lys(epsilon-thioAc)Leu-Ile | CHEMBL503595)
Affinity DataIC50: 2.38E+5nMAssay Description:Inhibition of recombinant SIRT2 preincubated for 5 mins before addition of substrate measured after 3 hrs by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed