BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.1M data for 1.3M Compounds and 9.6K Targets. Of those, 1.5M data for 698K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

If BindingDB was of value to your research, please take a moment to donate to this nonprofit project. Your donation will let us provide you with more data and improved service.

Donate Now
Advanced Search

To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

17 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
The extracellular entrance provides selectivity to serotonin 5-HT7 receptor antagonists with antidepressant-like behavior in vivo.EBI
Universidad Complutense De Madrid
Serotonin 5-HT6 receptor antagonists for the treatment of cognitive deficiency in Alzheimer's disease.EBI
Universidad Complutense De Madrid
Toxicological and pharmacological evaluation, antioxidant, ADMET and molecular modeling of selected racemic chromenotacrines {11-amino-12-aryl-8,9,10,12-tetrahydro-7H-chromeno[2,3-b]quinolin-3-ols} for the potential prevention and treatment of Alzheimer's disease.EBI
Universidad Complutense De Madrid
New serotonin 5-HT1A receptor agonists endowed with antinociceptive activity in vivo.EBI
Universidad Complutense De Madrid
Structure-activity relationship of a new series of reversible dual monoacylglycerol lipase/fatty acid amide hydrolase inhibitors.EBI
Universidad Complutense De Madrid
Benzimidazole derivatives as new serotonin 5-HT6 receptor antagonists. Molecular mechanisms of receptor inactivation.EBI
Universidad Complutense De Madrid
New serotonin 5-HT(1A) receptor agonists with neuroprotective effect against ischemic cell damage.EBI
Universidad Complutense De Madrid
Development of endocannabinoid-based chemical probes for the study of cannabinoid receptors.EBI
Universidad Complutense De Madrid
Development of non-peptide ligands of growth factor receptor-bound protein 2-SRC homology 2 domain using molecular modeling and NMR spectroscopy.EBI
Universidad Complutense De Madrid
Development of molecular probes for the human 5-HT(6) receptor.EBI
Universidad Complutense De Madrid
Synthesis of new serotonin 5-HT7 receptor ligands. Determinants of 5-HT7/5-HT1A receptor selectivity.EBI
Universidad Complutense De Madrid
The emerging role of mixed lineage kinase 3 (MLK3) and its potential as a target for neurodegenerative diseases therapies.EBI
Universidad Complutense De Madrid
Novel Antagonist of the Type 2 Lysophosphatidic Acid Receptor (LPAEBI
Universidad Complutense De Madrid
2-(Fluoromethoxy)-4'-(EBI
Universidad Complutense De Madrid
A Novel Agonist of the Type 1 Lysophosphatidic Acid Receptor (LPAEBI
Universidad Complutense De Madrid
A Potent Isoprenylcysteine Carboxylmethyltransferase (ICMT) Inhibitor Improves Survival in Ras-Driven Acute Myeloid Leukemia.EBI
Universidad Complutense De Madrid
A Positive Allosteric Modulator of the Serotonin 5-HTEBI
Universidad Complutense De Madrid