Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50019584
TargetMitogen-activated protein kinase kinase kinase 11(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM6760(CHEMBL281948 | methyl (15S,16R,18R)-16-hydroxy-15-...)
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human N-terminal HA-tagged wild type MLK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 11(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50620705(CHEMBL5413518)
Affinity DataIC50: 24nMAssay Description:Inhibition of MLK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 9(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM24942(methyl (15S,16R,18R)-10,23-bis[(ethylsulfanyl)meth...)
Affinity DataIC50: 38nMAssay Description:Inhibition of recombinant GST-tagged MLK1 (unknown origin) expressed in Baculovirus infected Sf21 cells incubated for 1 hr by affinity chromatography...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 9(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50620705(CHEMBL5413518)
Affinity DataIC50: 45nMAssay Description:Inhibition of MLK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 10(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM24942(methyl (15S,16R,18R)-10,23-bis[(ethylsulfanyl)meth...)
Affinity DataIC50: 51nMAssay Description:Inhibition of recombinant GST-tagged MLK2 (unknown origin) expressed in Baculovirus infected Sf21 cells incubated for 1 hr by affinity chromatography...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 11(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM24942(methyl (15S,16R,18R)-10,23-bis[(ethylsulfanyl)meth...)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of recombinant GST-tagged MLK3 (unknown origin) expressed in Baculovirus infected Sf21 cells incubated for 1 hr by affinity chromatography...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed