The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.5M data for 737K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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16 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Novel factor Xa inhibitors based on a benzoic acid scaffold and incorporating a neutral P1 ligand.EBI
Aventis Pharma Deutschland
Matrix metalloproteinase target family landscape: a chemometrical approach to ligand selectivity based on protein binding site analysis.EBI
Aventis Pharma Deutschland
QSAR-by-NMR: quantitative insights into structural determinants for binding affinity by analysis of 1H/15N chemical shift differences in MMP-3 ligands.EBI
Aventis Pharma Deutschland
Structure-based drug discovery using GPCR homology modeling: successful virtual screening for antagonists of the alpha1A adrenergic receptor.EBI
Aventis Pharma Deutschland
Structure-based design of amidinophenylurea-derivatives for factor VIIa inhibition.EBI
Aventis Pharma Deutschland
Pharmacophore-based search, synthesis, and biological evaluation of anthranilic amides as novel blockers of the Kv1.5 channel.EBI
Aventis Pharma Deutschland
Design, synthesis, and structure-activity relationship of a new class of amidinophenylurea-based factor VIIa inhibitors.EBI
Aventis Pharma Deutschland
Identification, synthesis, and activity of novel blockers of the voltage-gated potassium channel Kv1.5.EBI
Aventis Pharma Deutschland
Structural classification of protein kinases using 3D molecular interaction field analysis of their ligand binding sites: target family landscapes.EBI
Aventis Pharma Deutschland
Synthesis and activity of novel and selective I(Ks)-channel blockers.EBI
Aventis Pharma Deutschland
alpha(v)beta(3) Antagonists based on a central thiophene scaffold.EBI
Aventis Pharma Deutschland
Tricyclic heterocyclic compounds as phosphoinositide 3-kinase inhibitorsBDB
Karus Therapeutics
Substituted thiophene- and furan-fused azolopyrimidine-5-(6H)-one compoundsBDB
Dart Neuroscience (Cayman)
Bicyclo[1.1.1]pentane inhibitors of dual leucine zipper (DLK) kinase for the treatment of diseaseBDB
The University of Texas System
Bicyclic heteroarylaminoalkyl phenyl derivatives as PI3K inhibitorsBDB
Incyte
Tricyclic spiro compoundBDB
Ono Pharmaceutical