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TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50577453(CHEMBL4869861)
Affinity DataIC50: 50nMAssay Description:Inhibition of wild type human N-terminal His-tagged 12-LOX using arachidonic acid as substrate by UV-Vis spectroscopy analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700434(US20240336642, Compound 2 | 2-(3,5-Dichloro-2-meth...)
Affinity DataIC50: 63nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700696(US20240336642, Compound 101 | 5-((2-(2-((2-Methoxy...)
Affinity DataIC50: 72nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700603(US20240336642, Compound 8 | 2-(2,5-Dichloro-3-(tri...)
Affinity DataIC50: 81nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700683(US20240336642, Compound 88 | 5-((4-(Pyridin-4-ylme...)
Affinity DataIC50: 81nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700680(US20240336642, Compound 85 | 5-((4-((4-(2- Morphol...)
Affinity DataIC50: 82nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700433(US20240336642, Compound 1 | BDBM700639)
Affinity DataIC50: 90nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700447(US20240336642, Compound 4 | 2-(3,5-Dichloro-2-(flu...)
Affinity DataIC50: 97nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
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TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50009004(1-Phenyl-pyrazolidin-3-one(phenidone) | 1-phenylpy...)
Affinity DataIC50: 100nMAssay Description:Compound was tested in vitro for inhibition of 12-LO human plateletMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50009004(1-Phenyl-pyrazolidin-3-one(phenidone) | 1-phenylpy...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against human platelet 12-lipoxygenase was evaluatedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM22372(Nordihydroguaiaretic Acid | CHEMBL313972 | 4-[(2S,...)
Affinity DataIC50: 110nMAssay Description:Inhibition of human platelet-type 12-lipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700609(US20240336642, Compound 14 | 5-(allylamino)-2-(2,3...)
Affinity DataIC50: 110nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700692(US20240336642, Compound 97 | 5-((2-(2-(Pyridin-4- ...)
Affinity DataIC50: 110nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700697(US20240336642, Compound 102 | 5-((2-(2-((2-Fluorop...)
Affinity DataIC50: 110nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700433(US20240336642, Compound 1 | BDBM700639)
Affinity DataIC50: 120nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50158387(NSC-292213 | 4-[(3-carboxy-4-hydroxy-1-naphthyl)(o...)
Affinity DataIC50: 150nMAssay Description:Inhibition of human 12-hLOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50447181(CHEMBL3113197 | US10752581, Compound 67)
Affinity DataIC50: 160nMAssay Description:Inhibition of N-terminal His6-tagged human platelet 12-LOX using arachidonic acid as substrate by UV-vis spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50447181(CHEMBL3113197 | US10752581, Compound 67)
Affinity DataIC50: 160nMAssay Description:UV-vis cuvette-based assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700666(US20240336642, Compound 71 | 2-(2,3,5-Trichlorophe...)
Affinity DataIC50: 160nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700610(US20240336642, Compound 15 | (E)-5-(But-2-en-1-yla...)
Affinity DataIC50: 170nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700636(US20240336642, Compound 41 | 2-(3,5-Dichloro-2-met...)
Affinity DataIC50: 170nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50447202(CHEMBL3113193 | US10752581, Compound 63)
Affinity DataIC50: 180nMAssay Description:Inhibition of N-terminal His6-tagged human platelet 12-LOX using arachidonic acid as substrate by UV-vis spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM22372(Nordihydroguaiaretic Acid | CHEMBL313972 | 4-[(2S,...)
Affinity DataIC50: 180nMAssay Description:Inhibition of His-tagged human platelet 12-lipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50447202(CHEMBL3113193 | US10752581, Compound 63)
Affinity DataIC50: 180nMAssay Description:UV-vis cuvette-based assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700460(US20240336642, Compound 5 | 2-(3,5-Dichloro-2-meth...)
Affinity DataIC50: 180nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700504(US20240336642, Compound 6 | 2-(2,5-Dichloro-3-meth...)
Affinity DataIC50: 180nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700629(US20240336642, Compound 34 | 2-(3,5-Dichloro-2-met...)
Affinity DataIC50: 180nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700678(US20240336642, Compound 83 | 5-((2-(2-((2,6-Dimeth...)
Affinity DataIC50: 180nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700640(US20240336642, Compound 45 | (E)-5-((4-Methoxybut-...)
Affinity DataIC50: 190nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50221402(NSC-172033 | CHEMBL238624)
Affinity DataIC50: 210nMAssay Description:Inhibition of human 12-hLOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700641(US20240336642, Compound 46 | (E)-5-((5-Methoxypent...)
Affinity DataIC50: 210nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700682(US20240336642, Compound 87 | 5-((4-(Pyridin-4-ylme...)
Affinity DataIC50: 210nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50447180(CHEMBL3113198 | US10752581, Compound 68)
Affinity DataIC50: 220nMAssay Description:Inhibition of N-terminal His6-tagged human platelet 12-LOX using arachidonic acid as substrate by UV-vis spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50447180(CHEMBL3113198 | US10752581, Compound 68)
Affinity DataIC50: 220nMAssay Description:UV-vis cuvette-based assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700638(US20240336642, Compound 43 | 5-((4-(Benzyloxy)but-...)
Affinity DataIC50: 230nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700642(US20240336642, Compound 47 | (E)-5-((4-(Benzyloxy)...)
Affinity DataIC50: 230nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700681(US20240336642, Compound 86 | 5-((4-((4-(2- Morphol...)
Affinity DataIC50: 230nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50447184(CHEMBL3113169 | US10752581, Compound 39)
Affinity DataIC50: 240nMAssay Description:Inhibition of N-terminal His6-tagged human platelet 12-LOX using arachidonic acid as substrate by UV-vis spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50447184(CHEMBL3113169 | US10752581, Compound 39)
Affinity DataIC50: 240nMAssay Description:UV-vis cuvette-based assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700671(US20240336642, Compound 76 | 5-((2-(2-(Pyridin-3- ...)
Affinity DataIC50: 250nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM724209(US20250066345, Compound I-1)
Affinity DataIC50: 250nMAssay Description:Reaction buffers used for the lipoxygenase assay were as follows: 25 mM HEPES (pH 7.5), with 0.01% Triton X-100. 1 mM 12-HPETE or 1 mM 15-HPETE stock...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM724210(US20250066345, Compound I-2)
Affinity DataIC50: 250nMAssay Description:Reaction buffers used for the lipoxygenase assay were as follows: 25 mM HEPES (pH 7.5), with 0.01% Triton X-100. 1 mM 12-HPETE or 1 mM 15-HPETE stock...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM724211(US20250066345, Compound I-3)
Affinity DataIC50: 250nMAssay Description:Reaction buffers used for the lipoxygenase assay were as follows: 25 mM HEPES (pH 7.5), with 0.01% Triton X-100. 1 mM 12-HPETE or 1 mM 15-HPETE stock...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM724212(US20250066345, Compound I-4)
Affinity DataIC50: 250nMAssay Description:Reaction buffers used for the lipoxygenase assay were as follows: 25 mM HEPES (pH 7.5), with 0.01% Triton X-100. 1 mM 12-HPETE or 1 mM 15-HPETE stock...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM724213(US20250066345, Compound I-5)
Affinity DataIC50: 250nMAssay Description:Reaction buffers used for the lipoxygenase assay were as follows: 25 mM HEPES (pH 7.5), with 0.01% Triton X-100. 1 mM 12-HPETE or 1 mM 15-HPETE stock...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM724214(US20250066345, Compound I-6)
Affinity DataIC50: 250nMAssay Description:Reaction buffers used for the lipoxygenase assay were as follows: 25 mM HEPES (pH 7.5), with 0.01% Triton X-100. 1 mM 12-HPETE or 1 mM 15-HPETE stock...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM724215(US20250066345, Compound I-7)
Affinity DataIC50: 250nMAssay Description:Reaction buffers used for the lipoxygenase assay were as follows: 25 mM HEPES (pH 7.5), with 0.01% Triton X-100. 1 mM 12-HPETE or 1 mM 15-HPETE stock...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM724216(US20250066345, Compound I-8)
Affinity DataIC50: 250nMAssay Description:Reaction buffers used for the lipoxygenase assay were as follows: 25 mM HEPES (pH 7.5), with 0.01% Triton X-100. 1 mM 12-HPETE or 1 mM 15-HPETE stock...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM724220(US20250066345, Compound I-12)
Affinity DataIC50: 250nMAssay Description:Reaction buffers used for the lipoxygenase assay were as follows: 25 mM HEPES (pH 7.5), with 0.01% Triton X-100. 1 mM 12-HPETE or 1 mM 15-HPETE stock...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM724221(US20250066345, Compound I-13)
Affinity DataIC50: 250nMAssay Description:Reaction buffers used for the lipoxygenase assay were as follows: 25 mM HEPES (pH 7.5), with 0.01% Triton X-100. 1 mM 12-HPETE or 1 mM 15-HPETE stock...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

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