Compile Data Set for Download or QSAR
Report error Found 54 Enz. Inhib. hit(s) with all data for entry = 12646
TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM717604(US20250034169, Compound 53)
Affinity DataIC50: 4.30nMAssay Description:(1) Compound was prepared with DMSO, and diluted by 3-fold gradient with DMSO.(2) 0.1 μl of serial dilutions of the compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM717580(US20250034169, Compound 13)
Affinity DataIC50: 5.10nMAssay Description:(1) Compound was prepared with DMSO, and diluted by 3-fold gradient with DMSO.(2) 0.1 μl of serial dilutions of the compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM717609(US20250034169, Compound 67)
Affinity DataIC50: 5.40nMAssay Description:(1) Compound was prepared with DMSO, and diluted by 3-fold gradient with DMSO.(2) 0.1 μl of serial dilutions of the compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM717608(US20250034169, Compound 66)
Affinity DataIC50: 5.90nMAssay Description:(1) Compound was prepared with DMSO, and diluted by 3-fold gradient with DMSO.(2) 0.1 μl of serial dilutions of the compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM717610(US20250034169, Compound 68)
Affinity DataIC50: 6.5nMAssay Description:(1) Compound was prepared with DMSO, and diluted by 3-fold gradient with DMSO.(2) 0.1 μl of serial dilutions of the compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM717600(US20250034169, Compound 49)
Affinity DataIC50: 6.90nMAssay Description:(1) Compound was prepared with DMSO, and diluted by 3-fold gradient with DMSO.(2) 0.1 μl of serial dilutions of the compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM717611(US20250034169, Compound 78)
Affinity DataIC50: 7.5nMAssay Description:(1) Compound was prepared with DMSO, and diluted by 3-fold gradient with DMSO.(2) 0.1 μl of serial dilutions of the compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM717603(US20250034169, Compound 52)
Affinity DataIC50: 7.70nMAssay Description:(1) Compound was prepared with DMSO, and diluted by 3-fold gradient with DMSO.(2) 0.1 μl of serial dilutions of the compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM717577(US20250034169, Compound 10)
Affinity DataIC50: 8.70nMAssay Description:(1) Compound was prepared with DMSO, and diluted by 3-fold gradient with DMSO.(2) 0.1 μl of serial dilutions of the compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM717595(US20250034169, Compound 30)
Affinity DataIC50: 8.80nMAssay Description:(1) Compound was prepared with DMSO, and diluted by 3-fold gradient with DMSO.(2) 0.1 μl of serial dilutions of the compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM717576(US20250034169, Compound 9)
Affinity DataIC50: 8.80nMAssay Description:(1) Compound was prepared with DMSO, and diluted by 3-fold gradient with DMSO.(2) 0.1 μl of serial dilutions of the compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM717578(US20250034169, Compound 11)
Affinity DataIC50: 9.20nMAssay Description:(1) Compound was prepared with DMSO, and diluted by 3-fold gradient with DMSO.(2) 0.1 μl of serial dilutions of the compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM717579(US20250034169, Compound 12)
Affinity DataIC50: 9.70nMAssay Description:(1) Compound was prepared with DMSO, and diluted by 3-fold gradient with DMSO.(2) 0.1 μl of serial dilutions of the compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM717605(US20250034169, Compound 55)
Affinity DataIC50: 9.80nMAssay Description:(1) Compound was prepared with DMSO, and diluted by 3-fold gradient with DMSO.(2) 0.1 μl of serial dilutions of the compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM717607(US20250034169, Compound 65)
Affinity DataIC50: 9.90nMAssay Description:(1) Compound was prepared with DMSO, and diluted by 3-fold gradient with DMSO.(2) 0.1 μl of serial dilutions of the compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM717579(US20250034169, Compound 12)
Affinity DataIC50: 10.3nMAssay Description:(1) Compound was prepared with DMSO, and diluted by 3-fold gradient with DMSO.(2) 0.1 μl of serial dilutions of the compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM717602(US20250034169, Compound 51)
Affinity DataIC50: 11.1nMAssay Description:(1) Compound was prepared with DMSO, and diluted by 3-fold gradient with DMSO.(2) 0.1 μl of serial dilutions of the compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM717593(US20250034169, Compound 28)
Affinity DataIC50: 11.1nMAssay Description:(1) Compound was prepared with DMSO, and diluted by 3-fold gradient with DMSO.(2) 0.1 μl of serial dilutions of the compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM717580(US20250034169, Compound 13)
Affinity DataIC50: 11.3nMAssay Description:(1) Compound was prepared with DMSO, and diluted by 3-fold gradient with DMSO.(2) 0.1 μl of serial dilutions of the compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM717593(US20250034169, Compound 28)
Affinity DataIC50: 11.5nMAssay Description:(1) Compound was prepared with DMSO, and diluted by 3-fold gradient with DMSO.(2) 0.1 μl of serial dilutions of the compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM717608(US20250034169, Compound 66)
Affinity DataIC50: 11.7nMAssay Description:(1) Compound was prepared with DMSO, and diluted by 3-fold gradient with DMSO.(2) 0.1 μl of serial dilutions of the compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM717576(US20250034169, Compound 9)
Affinity DataIC50: 12.6nMAssay Description:(1) Compound was prepared with DMSO, and diluted by 3-fold gradient with DMSO.(2) 0.1 μl of serial dilutions of the compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM717595(US20250034169, Compound 30)
Affinity DataIC50: 13.4nMAssay Description:(1) Compound was prepared with DMSO, and diluted by 3-fold gradient with DMSO.(2) 0.1 μl of serial dilutions of the compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM717609(US20250034169, Compound 67)
Affinity DataIC50: 13.5nMAssay Description:(1) Compound was prepared with DMSO, and diluted by 3-fold gradient with DMSO.(2) 0.1 μl of serial dilutions of the compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM717581(US20250034169, Compound 24)
Affinity DataIC50: 13.6nMAssay Description:(1) Compound was prepared with DMSO, and diluted by 3-fold gradient with DMSO.(2) 0.1 μl of serial dilutions of the compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM717577(US20250034169, Compound 10)
Affinity DataIC50: 13.9nMAssay Description:(1) Compound was prepared with DMSO, and diluted by 3-fold gradient with DMSO.(2) 0.1 μl of serial dilutions of the compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM717604(US20250034169, Compound 53)
Affinity DataIC50: 14.6nMAssay Description:(1) Compound was prepared with DMSO, and diluted by 3-fold gradient with DMSO.(2) 0.1 μl of serial dilutions of the compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM717594(US20250034169, Compound 29)
Affinity DataIC50: 14.7nMAssay Description:(1) Compound was prepared with DMSO, and diluted by 3-fold gradient with DMSO.(2) 0.1 μl of serial dilutions of the compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM717605(US20250034169, Compound 55)
Affinity DataIC50: 14.8nMAssay Description:(1) Compound was prepared with DMSO, and diluted by 3-fold gradient with DMSO.(2) 0.1 μl of serial dilutions of the compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM717585(US20250034169, Compound 25)
Affinity DataIC50: 15nMAssay Description:(1) Compound was prepared with DMSO, and diluted by 3-fold gradient with DMSO.(2) 0.1 μl of serial dilutions of the compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM717581(US20250034169, Compound 24)
Affinity DataIC50: 15.1nMAssay Description:(1) Compound was prepared with DMSO, and diluted by 3-fold gradient with DMSO.(2) 0.1 μl of serial dilutions of the compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM717599(US20250034169, Compound 44)
Affinity DataIC50: 15.2nMAssay Description:(1) Compound was prepared with DMSO, and diluted by 3-fold gradient with DMSO.(2) 0.1 μl of serial dilutions of the compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM717603(US20250034169, Compound 52)
Affinity DataIC50: 15.2nMAssay Description:(1) Compound was prepared with DMSO, and diluted by 3-fold gradient with DMSO.(2) 0.1 μl of serial dilutions of the compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM717606(US20250034169, Compound 56)
Affinity DataIC50: 15.7nMAssay Description:(1) Compound was prepared with DMSO, and diluted by 3-fold gradient with DMSO.(2) 0.1 μl of serial dilutions of the compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM717600(US20250034169, Compound 49)
Affinity DataIC50: 15.7nMAssay Description:(1) Compound was prepared with DMSO, and diluted by 3-fold gradient with DMSO.(2) 0.1 μl of serial dilutions of the compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM717594(US20250034169, Compound 29)
Affinity DataIC50: 15.9nMAssay Description:(1) Compound was prepared with DMSO, and diluted by 3-fold gradient with DMSO.(2) 0.1 μl of serial dilutions of the compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM717598(US20250034169, Compound 43)
Affinity DataIC50: 16.3nMAssay Description:(1) Compound was prepared with DMSO, and diluted by 3-fold gradient with DMSO.(2) 0.1 μl of serial dilutions of the compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM717610(US20250034169, Compound 68)
Affinity DataIC50: 16.6nMAssay Description:(1) Compound was prepared with DMSO, and diluted by 3-fold gradient with DMSO.(2) 0.1 μl of serial dilutions of the compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM717585(US20250034169, Compound 25)
Affinity DataIC50: 16.8nMAssay Description:(1) Compound was prepared with DMSO, and diluted by 3-fold gradient with DMSO.(2) 0.1 μl of serial dilutions of the compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM717611(US20250034169, Compound 78)
Affinity DataIC50: 17.3nMAssay Description:(1) Compound was prepared with DMSO, and diluted by 3-fold gradient with DMSO.(2) 0.1 μl of serial dilutions of the compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM717606(US20250034169, Compound 56)
Affinity DataIC50: 18.5nMAssay Description:(1) Compound was prepared with DMSO, and diluted by 3-fold gradient with DMSO.(2) 0.1 μl of serial dilutions of the compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM717607(US20250034169, Compound 65)
Affinity DataIC50: 18.5nMAssay Description:(1) Compound was prepared with DMSO, and diluted by 3-fold gradient with DMSO.(2) 0.1 μl of serial dilutions of the compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM717601(US20250034169, Compound 50)
Affinity DataIC50: 19.1nMAssay Description:(1) Compound was prepared with DMSO, and diluted by 3-fold gradient with DMSO.(2) 0.1 μl of serial dilutions of the compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM717578(US20250034169, Compound 11)
Affinity DataIC50: 19.8nMAssay Description:(1) Compound was prepared with DMSO, and diluted by 3-fold gradient with DMSO.(2) 0.1 μl of serial dilutions of the compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM717602(US20250034169, Compound 51)
Affinity DataIC50: 20.8nMAssay Description:(1) Compound was prepared with DMSO, and diluted by 3-fold gradient with DMSO.(2) 0.1 μl of serial dilutions of the compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM717612(US20250034169, Compound 84)
Affinity DataIC50: 20.8nMAssay Description:(1) Compound was prepared with DMSO, and diluted by 3-fold gradient with DMSO.(2) 0.1 μl of serial dilutions of the compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM717597(US20250034169, Compound 41)
Affinity DataIC50: 22nMAssay Description:(1) Compound was prepared with DMSO, and diluted by 3-fold gradient with DMSO.(2) 0.1 μl of serial dilutions of the compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM717598(US20250034169, Compound 43)
Affinity DataIC50: 24.1nMAssay Description:(1) Compound was prepared with DMSO, and diluted by 3-fold gradient with DMSO.(2) 0.1 μl of serial dilutions of the compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM717596(US20250034169, Compound 31)
Affinity DataIC50: 24.6nMAssay Description:(1) Compound was prepared with DMSO, and diluted by 3-fold gradient with DMSO.(2) 0.1 μl of serial dilutions of the compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Sunshine Lake Pharma Co.

US Patent
LigandPNGBDBM717612(US20250034169, Compound 84)
Affinity DataIC50: 29.6nMAssay Description:(1) Compound was prepared with DMSO, and diluted by 3-fold gradient with DMSO.(2) 0.1 μl of serial dilutions of the compound was added to a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

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