Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 12529
TargetCytochrome P450 2C8(Human)
Nicoya Therapeutics (Shanghai) Co.

US Patent
LigandPNGBDBM50175523(4''-(2-Butyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-...)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibitory Effects on Activities of Cytochrome P450 Isozymes (CYP1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A4) from Human Liver Microsomes. A total of si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2025
Entry Details
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TargetCytochrome P450 3A4(Human)
Nicoya Therapeutics (Shanghai) Co.

US Patent
LigandPNGBDBM50175523(4''-(2-Butyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-...)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibitory Effects on Activities of Cytochrome P450 Isozymes (CYP1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A4) from Human Liver Microsomes. A total of si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2025
Entry Details
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TargetCytochrome P450 3A4(Human)
Nicoya Therapeutics (Shanghai) Co.

US Patent
LigandPNGBDBM707647(US20240417395, Example 3)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibitory Effects on Activities of Cytochrome P450 Isozymes (CYP1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A4) from Human Liver Microsomes. A total of si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/1/2025
Entry Details
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TargetCytochrome P450 2D6(Human)
Nicoya Therapeutics (Shanghai) Co.

US Patent
LigandPNGBDBM707713(US20240417395, Example 7)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory Effects on Activities of Cytochrome P450 Isozymes (CYP1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A4) from Human Liver Microsomes. A total of si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/1/2025
Entry Details
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TargetCytochrome P450 2D6(Human)
Nicoya Therapeutics (Shanghai) Co.

US Patent
LigandPNGBDBM50175523(4''-(2-Butyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory Effects on Activities of Cytochrome P450 Isozymes (CYP1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A4) from Human Liver Microsomes. A total of si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2025
Entry Details
Go to US Patent

TargetCytochrome P450 2C19(Human)
Nicoya Therapeutics (Shanghai) Co.

US Patent
LigandPNGBDBM50175523(4''-(2-Butyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory Effects on Activities of Cytochrome P450 Isozymes (CYP1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A4) from Human Liver Microsomes. A total of si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2025
Entry Details
Go to US Patent

TargetCytochrome P450 2C9(Human)
Nicoya Therapeutics (Shanghai) Co.

US Patent
LigandPNGBDBM50175523(4''-(2-Butyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory Effects on Activities of Cytochrome P450 Isozymes (CYP1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A4) from Human Liver Microsomes. A total of si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2025
Entry Details
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TargetCytochrome P450 1A2(Human)
Nicoya Therapeutics (Shanghai) Co.

US Patent
LigandPNGBDBM50175523(4''-(2-Butyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory Effects on Activities of Cytochrome P450 Isozymes (CYP1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A4) from Human Liver Microsomes. A total of si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2025
Entry Details
Go to US Patent

TargetCytochrome P450 2C8(Human)
Nicoya Therapeutics (Shanghai) Co.

US Patent
LigandPNGBDBM707713(US20240417395, Example 7)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory Effects on Activities of Cytochrome P450 Isozymes (CYP1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A4) from Human Liver Microsomes. A total of si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/1/2025
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Nicoya Therapeutics (Shanghai) Co.

US Patent
LigandPNGBDBM707713(US20240417395, Example 7)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory Effects on Activities of Cytochrome P450 Isozymes (CYP1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A4) from Human Liver Microsomes. A total of si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/1/2025
Entry Details
Go to US Patent

TargetCytochrome P450 1A2(Human)
Nicoya Therapeutics (Shanghai) Co.

US Patent
LigandPNGBDBM707647(US20240417395, Example 3)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory Effects on Activities of Cytochrome P450 Isozymes (CYP1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A4) from Human Liver Microsomes. A total of si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/1/2025
Entry Details
Go to US Patent

TargetCytochrome P450 2C19(Human)
Nicoya Therapeutics (Shanghai) Co.

US Patent
LigandPNGBDBM707713(US20240417395, Example 7)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory Effects on Activities of Cytochrome P450 Isozymes (CYP1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A4) from Human Liver Microsomes. A total of si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/1/2025
Entry Details
Go to US Patent

TargetCytochrome P450 2C9(Human)
Nicoya Therapeutics (Shanghai) Co.

US Patent
LigandPNGBDBM707713(US20240417395, Example 7)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory Effects on Activities of Cytochrome P450 Isozymes (CYP1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A4) from Human Liver Microsomes. A total of si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/1/2025
Entry Details
Go to US Patent

TargetCytochrome P450 1A2(Human)
Nicoya Therapeutics (Shanghai) Co.

US Patent
LigandPNGBDBM707713(US20240417395, Example 7)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory Effects on Activities of Cytochrome P450 Isozymes (CYP1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A4) from Human Liver Microsomes. A total of si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/1/2025
Entry Details
Go to US Patent

TargetCytochrome P450 2C8(Human)
Nicoya Therapeutics (Shanghai) Co.

US Patent
LigandPNGBDBM707647(US20240417395, Example 3)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory Effects on Activities of Cytochrome P450 Isozymes (CYP1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A4) from Human Liver Microsomes. A total of si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/1/2025
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Nicoya Therapeutics (Shanghai) Co.

US Patent
LigandPNGBDBM707647(US20240417395, Example 3)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory Effects on Activities of Cytochrome P450 Isozymes (CYP1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A4) from Human Liver Microsomes. A total of si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/1/2025
Entry Details
Go to US Patent

TargetCytochrome P450 2C19(Human)
Nicoya Therapeutics (Shanghai) Co.

US Patent
LigandPNGBDBM707647(US20240417395, Example 3)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory Effects on Activities of Cytochrome P450 Isozymes (CYP1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A4) from Human Liver Microsomes. A total of si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/1/2025
Entry Details
Go to US Patent

TargetCytochrome P450 2C9(Human)
Nicoya Therapeutics (Shanghai) Co.

US Patent
LigandPNGBDBM707647(US20240417395, Example 3)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory Effects on Activities of Cytochrome P450 Isozymes (CYP1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A4) from Human Liver Microsomes. A total of si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/1/2025
Entry Details
Go to US Patent