Compile Data Set for Download or QSAR
Report error Found 106 Enz. Inhib. hit(s) with all data for entry = 12397
TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700434(US20240336642, Compound 2 | 2-(3,5-Dichloro-2-meth...)
Affinity DataIC50: 63nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
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TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700696(US20240336642, Compound 101 | 5-((2-(2-((2-Methoxy...)
Affinity DataIC50: 72nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700603(US20240336642, Compound 8 | 2-(2,5-Dichloro-3-(tri...)
Affinity DataIC50: 81nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
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TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700683(US20240336642, Compound 88 | 5-((4-(Pyridin-4-ylme...)
Affinity DataIC50: 81nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700680(US20240336642, Compound 85 | 5-((4-((4-(2- Morphol...)
Affinity DataIC50: 82nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700433(US20240336642, Compound 1 | BDBM700639)
Affinity DataIC50: 90nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700447(US20240336642, Compound 4 | 2-(3,5-Dichloro-2-(flu...)
Affinity DataIC50: 97nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
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TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700609(US20240336642, Compound 14 | 5-(allylamino)-2-(2,3...)
Affinity DataIC50: 110nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700692(US20240336642, Compound 97 | 5-((2-(2-(Pyridin-4- ...)
Affinity DataIC50: 110nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700697(US20240336642, Compound 102 | 5-((2-(2-((2-Fluorop...)
Affinity DataIC50: 110nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700433(US20240336642, Compound 1 | BDBM700639)
Affinity DataIC50: 120nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700666(US20240336642, Compound 71 | 2-(2,3,5-Trichlorophe...)
Affinity DataIC50: 160nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700610(US20240336642, Compound 15 | (E)-5-(But-2-en-1-yla...)
Affinity DataIC50: 170nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700636(US20240336642, Compound 41 | 2-(3,5-Dichloro-2-met...)
Affinity DataIC50: 170nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700460(US20240336642, Compound 5 | 2-(3,5-Dichloro-2-meth...)
Affinity DataIC50: 180nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700504(US20240336642, Compound 6 | 2-(2,5-Dichloro-3-meth...)
Affinity DataIC50: 180nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700629(US20240336642, Compound 34 | 2-(3,5-Dichloro-2-met...)
Affinity DataIC50: 180nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700678(US20240336642, Compound 83 | 5-((2-(2-((2,6-Dimeth...)
Affinity DataIC50: 180nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700640(US20240336642, Compound 45 | (E)-5-((4-Methoxybut-...)
Affinity DataIC50: 190nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700641(US20240336642, Compound 46 | (E)-5-((5-Methoxypent...)
Affinity DataIC50: 210nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700682(US20240336642, Compound 87 | 5-((4-(Pyridin-4-ylme...)
Affinity DataIC50: 210nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700638(US20240336642, Compound 43 | 5-((4-(Benzyloxy)but-...)
Affinity DataIC50: 230nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700642(US20240336642, Compound 47 | (E)-5-((4-(Benzyloxy)...)
Affinity DataIC50: 230nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700681(US20240336642, Compound 86 | 5-((4-((4-(2- Morphol...)
Affinity DataIC50: 230nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700671(US20240336642, Compound 76 | 5-((2-(2-(Pyridin-3- ...)
Affinity DataIC50: 250nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700676(US20240336642, Compound 81 | 5-((2-(2-(Phenylamino...)
Affinity DataIC50: 260nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700690(US20240336642, Compound 95 | 5-((2-(2- (Methyl(phe...)
Affinity DataIC50: 260nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700635(US20240336642, Compound 40 | 2-(3,5-Dichloro-2-(di...)
Affinity DataIC50: 290nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700689(US20240336642, Compound 94 | 2-(2,3,5-Trichlorophe...)
Affinity DataIC50: 300nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700619(US20240336642, Compound 24 | 2-(3,5-Dichloro-2-met...)
Affinity DataIC50: 320nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700446(US20240336642, Compound 3 | 2-(3,5-Dichloro-2-fluo...)
Affinity DataIC50: 330nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700664(US20240336642, Compound 69 | 5-((2-(2-Ethoxyethoxy...)
Affinity DataIC50: 330nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700637(US20240336642, Compound 42 | 2-(2,5-Dichloro-3-(tr...)
Affinity DataIC50: 350nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700677(US20240336642, Compound 82 | 5-((2-(2-(Pyrimidin-5...)
Affinity DataIC50: 360nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700634(US20240336642, Compound 39 | 5-((2-Methoxyethyl)am...)
Affinity DataIC50: 370nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700604(US20240336642, Compound 9 | 2-(5-Chloro-3-methoxy-...)
Affinity DataIC50: 380nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700605(US20240336642, Compound 10 | 2-(2,3-Dichloro-5-met...)
Affinity DataIC50: 380nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700614(US20240336642, Compound 19 | 2-(3,5-Dichloro-2-met...)
Affinity DataIC50: 460nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700668(US20240336642, Compound 73 | 5-((2-(2-(Methyl(2,2,...)
Affinity DataIC50: 470nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700679(US20240336642, Compound 84 | 5-((2-(2-((3-Fluoropy...)
Affinity DataIC50: 490nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700617(US20240336642, Compound 22 | 5-((5-Hydroxypentyl)a...)
Affinity DataIC50: 510nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700622(US20240336642, Compound 27 | 2-(2,5-Dichloro-3-(tr...)
Affinity DataIC50: 550nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700627(US20240336642, Compound 32)
Affinity DataIC50: 610nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700643(US20240336642, Compound 48 | 5-((4-(2-Methoxyethox...)
Affinity DataIC50: 620nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700628(US20240336642, Compound 33 | 2-(3,5-Dichloro-2-(di...)
Affinity DataIC50: 650nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700644(US20240336642, Compound 49 | 5-((2-(2-Isopropoxyet...)
Affinity DataIC50: 660nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700625(US20240336642, Compound 30 | 2-(3,5-Dichloro-2-met...)
Affinity DataIC50: 670nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM50011735(CHEMBL3262908 | US20240336642, Example 2.3)
Affinity DataIC50: 670nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700621(US20240336642, Compound 26 | 2-(2,5-Dichloro-3-met...)
Affinity DataIC50: 800nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700606(US20240336642, Compound 11 | 2-(2,3-Dichloro-5-flu...)
Affinity DataIC50: 870nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

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