Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 11138
TargetSphingosine 1-phosphate receptor 5(Human)
Beijing Foreland Pharma

US Patent
LigandPNGBDBM50158348((2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihy...)
Affinity DataEC50:  23nMAssay Description:The sample to be tested was dissolved in DMSO and diluted with detection buffer solution in 3-fold dilution. A reagent and a positive control were di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetSphingosine 1-phosphate receptor 5(Human)
Beijing Foreland Pharma

US Patent
LigandPNGBDBM594032(US11584726, Example 13 | (S)-(2-amino-7-(5-(3,4-di...)
Affinity DataEC50: >1.00E+4nMAssay Description:The sample to be tested was dissolved in DMSO and diluted with detection buffer solution in 3-fold dilution. A reagent and a positive control were di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
Go to US Patent

TargetSphingosine 1-phosphate receptor 5(Human)
Beijing Foreland Pharma

US Patent
LigandPNGBDBM594033(US11584726, Example 3 | (S)-5-(5-(7-amino-7-(hydro...)
Affinity DataEC50:  250nMAssay Description:The sample to be tested was dissolved in DMSO and diluted with detection buffer solution in 3-fold dilution. A reagent and a positive control were di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Beijing Foreland Pharma

US Patent
LigandPNGBDBM594034(US11584726, Example 14 | (S)-(2-amino-7-(5-(4-isop...)
Affinity DataIC50: 870nMAssay Description:HEK293 engineering cells stably expressed with hERG potassium channel were used to test the compounds. Patch Clamp Detection: The cells were separate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Beijing Foreland Pharma

US Patent
LigandPNGBDBM594032(US11584726, Example 13 | (S)-(2-amino-7-(5-(3,4-di...)
Affinity DataIC50: 1.20E+3nMAssay Description:HEK293 engineering cells stably expressed with hERG potassium channel were used to test the compounds. Patch Clamp Detection: The cells were separate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Beijing Foreland Pharma

US Patent
LigandPNGBDBM594033(US11584726, Example 3 | (S)-5-(5-(7-amino-7-(hydro...)
Affinity DataIC50: 7.80E+3nMAssay Description:HEK293 engineering cells stably expressed with hERG potassium channel were used to test the compounds. Patch Clamp Detection: The cells were separate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
Go to US Patent