Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 11378
TargetMetallo-beta-lactamase type 2 [29-270](Pseudomonas aeruginosa (g-Proteobacteria))
The University of Hong Kong

US Patent
LigandPNGBDBM610686(US10624871, Compound Bi(NO3)3)
Affinity DataIC50: 1.89E+3nMAssay Description:Freshly prepared Zn2-NDM-1 (50 nM) or Zn2-VIM-2 were first incubated with various concentrations of Bi(III) compounds for 1 h at 25° C. The assay was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2023
Entry Details
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PDB3D3D Structure (crystal)
TargetMetallo-beta-lactamase VIM-2 [21-266](Pseudomonas aeruginosa (g-Proteobacteria))
The University of Hong Kong

US Patent
LigandPNGBDBM610686(US10624871, Compound Bi(NO3)3)
Affinity DataIC50: 2.45E+3nMAssay Description:Freshly prepared Zn2-NDM-1 (50 nM) or Zn2-VIM-2 were first incubated with various concentrations of Bi(III) compounds for 1 h at 25° C. The assay was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2023
Entry Details
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TargetMetallo-beta-lactamase type 2 [29-270](Pseudomonas aeruginosa (g-Proteobacteria))
The University of Hong Kong

US Patent
LigandPNGBDBM610684(US10624871, Compound 12)
Affinity DataIC50: 3.86E+3nMAssay Description:Freshly prepared Zn2-NDM-1 (50 nM) or Zn2-VIM-2 were first incubated with various concentrations of Bi(III) compounds for 1 h at 25° C. The assay was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2023
Entry Details
Go to US Patent

TargetMetallo-beta-lactamase type 2 [29-270](Pseudomonas aeruginosa (g-Proteobacteria))
The University of Hong Kong

US Patent
LigandPNGBDBM610683(US10624871, Compound 10)
Affinity DataIC50: 5.83E+3nMAssay Description:Freshly prepared Zn2-NDM-1 (50 nM) or Zn2-VIM-2 were first incubated with various concentrations of Bi(III) compounds for 1 h at 25° C. The assay was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2023
Entry Details
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TargetMetallo-beta-lactamase VIM-2 [21-266](Pseudomonas aeruginosa (g-Proteobacteria))
The University of Hong Kong

US Patent
LigandPNGBDBM610687(US10624871, Compound 15)
Affinity DataIC50: 6.17E+3nMAssay Description:Freshly prepared Zn2-NDM-1 (50 nM) or Zn2-VIM-2 were first incubated with various concentrations of Bi(III) compounds for 1 h at 25° C. The assay was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2023
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetMetallo-beta-lactamase type 2 [29-270](Pseudomonas aeruginosa (g-Proteobacteria))
The University of Hong Kong

US Patent
LigandPNGBDBM610685(US10624871, Compound 21)
Affinity DataIC50: 1.77E+4nMAssay Description:Freshly prepared Zn2-NDM-1 (50 nM) or Zn2-VIM-2 were first incubated with various concentrations of Bi(III) compounds for 1 h at 25° C. The assay was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2023
Entry Details
Go to US Patent

TargetMetallo-beta-lactamase VIM-2 [21-266](Pseudomonas aeruginosa (g-Proteobacteria))
The University of Hong Kong

US Patent
LigandPNGBDBM610683(US10624871, Compound 10)
Affinity DataIC50: 4.45E+4nMAssay Description:Freshly prepared Zn2-NDM-1 (50 nM) or Zn2-VIM-2 were first incubated with various concentrations of Bi(III) compounds for 1 h at 25° C. The assay was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2023
Entry Details
Go to US Patent