Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50019586
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50620778(CHEMBL5433167)
Affinity DataIC50: 1.55E+3nMAssay Description:Inhibition of NLRP3-dependent pyroptosis in PMA-differentiated human THP-1 cells assessed as inhibition of LPS/ATP-induced cell death pretreated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50620779(CHEMBL5435112)
Affinity DataIC50: 1.85E+3nMAssay Description:Inhibition of NLRP3-dependent pyroptosis in PMA-differentiated human THP-1 cells assessed as inhibition of LPS/ATP-induced cell death pretreated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50620778(CHEMBL5433167)
Affinity DataIC50: 1.66E+4nMAssay Description:Inhibition of NLRP3 inflammasome activation in PMA-differentiated human THP-1 cells assessed as inhibition of LPS/ATP-induced IL-1 beta release pretr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50620779(CHEMBL5435112)
Affinity DataIC50: 3.26E+4nMAssay Description:Inhibition of NLRP3 inflammasome activation in PMA-differentiated human THP-1 cells assessed as inhibition of LPS/ATP-induced IL-1 beta release pretr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed