Assay Method Information

Assay Name:  ChEMBL_2326165
Description:  Inhibition of NLRP3-dependent pyroptosis in PMA-differentiated human THP-1 cells assessed as inhibition of LPS/ATP-induced cell death pretreated for 4 hrs with LPS followed by incubation with compound for 1 hr and later treated with ATP for 1.5 hrs by LDH assay
Affinity data for this assay
 

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