Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 50007696
TargetHistone acetyltransferase p300(Human)
Avera Institute For Human Genetics

Curated by ChEMBL
LigandPNGBDBM50467836(CHEMBL4282264)
Affinity DataIC50: 60nMAssay Description:Inhibition of p300 HAT domain (unknown origin) using Biotin-C6-GRGKGGKGLGKGGAK as substrate pretreated with enzyme for 30 mins followed by incubation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone acetyltransferase p300(Human)
Avera Institute For Human Genetics

Curated by ChEMBL
LigandPNGBDBM50255529(Ac-Lys(CoA)-NH2 | CHEMBL505121)
Affinity DataIC50: 500nMAssay Description:Inhibition of N-terminal His-tagged human recombinant p300 catalytic domain (1284-1673 residues) using histone H4-8 peptide and [14C]acetyl CoA as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Avera Institute For Human Genetics

Curated by ChEMBL
LigandPNGBDBM50511789(CHEMBL4474132)
Affinity DataIC50: 620nMAssay Description:Inhibition of recombinant human GST-tagged p300 HAT domain (1195 to 1673 residues) expressed in Escherichia coli BL21 codon plus cells using Histone ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetCREB-binding protein(Human)
Avera Institute For Human Genetics

Curated by ChEMBL
LigandPNGBDBM50511789(CHEMBL4474132)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of recombinant human GST-tagged CBP HAT domain expressed in Escherichia coli BL21 codon plus cells using Histone H3 peptide (1 to 21) and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Avera Institute For Human Genetics

Curated by ChEMBL
LigandPNGBDBM50511794(CHEMBL4563856)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of recombinant human GST-tagged p300 HAT domain (1195 to 1673 residues) expressed in Escherichia coli BL21 codon plus cells using Histone ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Avera Institute For Human Genetics

Curated by ChEMBL
LigandPNGBDBM50511823(CHEMBL4573471)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of recombinant human GST-tagged p300 HAT domain (1195 to 1673 residues) expressed in Escherichia coli BL21 codon plus cells using Histone ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Avera Institute For Human Genetics

Curated by ChEMBL
LigandPNGBDBM50511800(CHEMBL4440850)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of recombinant human GST-tagged p300 HAT domain (1195 to 1673 residues) expressed in Escherichia coli BL21 codon plus cells using Histone ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Avera Institute For Human Genetics

Curated by ChEMBL
LigandPNGBDBM50511796(CHEMBL4513688)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of recombinant human GST-tagged p300 HAT domain (1195 to 1673 residues) expressed in Escherichia coli BL21 codon plus cells using Histone ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Avera Institute For Human Genetics

Curated by ChEMBL
LigandPNGBDBM50511819(CHEMBL4462417)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of recombinant human GST-tagged p300 HAT domain (1195 to 1673 residues) expressed in Escherichia coli BL21 codon plus cells using Histone ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Avera Institute For Human Genetics

Curated by ChEMBL
LigandPNGBDBM50151658(CHEMBL3775671)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant p300 catalytic domain (unknown origin) using histone H3 N-terminal peptide as substrate in presence of acetyl CoA by fluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Avera Institute For Human Genetics

Curated by ChEMBL
LigandPNGBDBM50511807(CHEMBL4447919)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant human GST-tagged p300 HAT domain (1195 to 1673 residues) expressed in Escherichia coli BL21 codon plus cells using Histone ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Avera Institute For Human Genetics

Curated by ChEMBL
LigandPNGBDBM50511822(CHEMBL4532286)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of recombinant human GST-tagged p300 HAT domain (1195 to 1673 residues) expressed in Escherichia coli BL21 codon plus cells using Histone ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Avera Institute For Human Genetics

Curated by ChEMBL
LigandPNGBDBM50511812(CHEMBL4455410)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of recombinant human GST-tagged p300 HAT domain (1195 to 1673 residues) expressed in Escherichia coli BL21 codon plus cells using Histone ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Avera Institute For Human Genetics

Curated by ChEMBL
LigandPNGBDBM50511801(CHEMBL4564485)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of recombinant human GST-tagged p300 HAT domain (1195 to 1673 residues) expressed in Escherichia coli BL21 codon plus cells using Histone ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Avera Institute For Human Genetics

Curated by ChEMBL
LigandPNGBDBM50511821(CHEMBL4517313)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of recombinant human GST-tagged p300 HAT domain (1195 to 1673 residues) expressed in Escherichia coli BL21 codon plus cells using Histone ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Avera Institute For Human Genetics

Curated by ChEMBL
LigandPNGBDBM50511803(CHEMBL4472420)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of recombinant human GST-tagged p300 HAT domain (1195 to 1673 residues) expressed in Escherichia coli BL21 codon plus cells using Histone ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Avera Institute For Human Genetics

Curated by ChEMBL
LigandPNGBDBM50511806(CHEMBL4532765)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of recombinant human GST-tagged p300 HAT domain (1195 to 1673 residues) expressed in Escherichia coli BL21 codon plus cells using Histone ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Avera Institute For Human Genetics

Curated by ChEMBL
LigandPNGBDBM50511795(CHEMBL4454456)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human GST-tagged p300 HAT domain (1195 to 1673 residues) expressed in Escherichia coli BL21 codon plus cells using Histone ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Avera Institute For Human Genetics

Curated by ChEMBL
LigandPNGBDBM50511791(CHEMBL4483638)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of recombinant human GST-tagged p300 HAT domain (1195 to 1673 residues) expressed in Escherichia coli BL21 codon plus cells using Histone ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Avera Institute For Human Genetics

Curated by ChEMBL
LigandPNGBDBM50511805(CHEMBL4590021)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of recombinant human GST-tagged p300 HAT domain (1195 to 1673 residues) expressed in Escherichia coli BL21 codon plus cells using Histone ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Avera Institute For Human Genetics

Curated by ChEMBL
LigandPNGBDBM50511811(CHEMBL4460914)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of recombinant human GST-tagged p300 HAT domain (1195 to 1673 residues) expressed in Escherichia coli BL21 codon plus cells using Histone ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Avera Institute For Human Genetics

Curated by ChEMBL
LigandPNGBDBM50511804(CHEMBL4586718)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of recombinant human GST-tagged p300 HAT domain (1195 to 1673 residues) expressed in Escherichia coli BL21 codon plus cells using Histone ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Avera Institute For Human Genetics

Curated by ChEMBL
LigandPNGBDBM50511797(CHEMBL4470554)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of recombinant human GST-tagged p300 HAT domain (1195 to 1673 residues) expressed in Escherichia coli BL21 codon plus cells using Histone ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Avera Institute For Human Genetics

Curated by ChEMBL
LigandPNGBDBM50511816(CHEMBL4579841)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of recombinant human GST-tagged p300 HAT domain (1195 to 1673 residues) expressed in Escherichia coli BL21 codon plus cells using Histone ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Avera Institute For Human Genetics

Curated by ChEMBL
LigandPNGBDBM50511820(CHEMBL4535532)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of recombinant human GST-tagged p300 HAT domain (1195 to 1673 residues) expressed in Escherichia coli BL21 codon plus cells using Histone ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Avera Institute For Human Genetics

Curated by ChEMBL
LigandPNGBDBM50511802(CHEMBL4462134)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of recombinant human GST-tagged p300 HAT domain (1195 to 1673 residues) expressed in Escherichia coli BL21 codon plus cells using Histone ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Avera Institute For Human Genetics

Curated by ChEMBL
LigandPNGBDBM50511810(CHEMBL4516433)
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of recombinant human GST-tagged p300 HAT domain (1195 to 1673 residues) expressed in Escherichia coli BL21 codon plus cells using Histone ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Avera Institute For Human Genetics

Curated by ChEMBL
LigandPNGBDBM50511818(CHEMBL4575922)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human GST-tagged p300 HAT domain (1195 to 1673 residues) expressed in Escherichia coli BL21 codon plus cells using Histone ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Avera Institute For Human Genetics

Curated by ChEMBL
LigandPNGBDBM50511824(CHEMBL4451922)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human GST-tagged p300 HAT domain (1195 to 1673 residues) expressed in Escherichia coli BL21 codon plus cells using Histone ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Avera Institute For Human Genetics

Curated by ChEMBL
LigandPNGBDBM50511817(CHEMBL4520507)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human GST-tagged p300 HAT domain (1195 to 1673 residues) expressed in Escherichia coli BL21 codon plus cells using Histone ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Avera Institute For Human Genetics

Curated by ChEMBL
LigandPNGBDBM50511809(CHEMBL4465795)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human GST-tagged p300 HAT domain (1195 to 1673 residues) expressed in Escherichia coli BL21 codon plus cells using Histone ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Avera Institute For Human Genetics

Curated by ChEMBL
LigandPNGBDBM50511815(CHEMBL4516301)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human GST-tagged p300 HAT domain (1195 to 1673 residues) expressed in Escherichia coli BL21 codon plus cells using Histone ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Avera Institute For Human Genetics

Curated by ChEMBL
LigandPNGBDBM50511814(CHEMBL4441263)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human GST-tagged p300 HAT domain (1195 to 1673 residues) expressed in Escherichia coli BL21 codon plus cells using Histone ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Avera Institute For Human Genetics

Curated by ChEMBL
LigandPNGBDBM50511813(CHEMBL4555712)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human GST-tagged p300 HAT domain (1195 to 1673 residues) expressed in Escherichia coli BL21 codon plus cells using Histone ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Avera Institute For Human Genetics

Curated by ChEMBL
LigandPNGBDBM50511788(CHEMBL4468294)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human GST-tagged p300 HAT domain (1195 to 1673 residues) expressed in Escherichia coli BL21 codon plus cells using Histone ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Avera Institute For Human Genetics

Curated by ChEMBL
LigandPNGBDBM50511808(CHEMBL4574051)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human GST-tagged p300 HAT domain (1195 to 1673 residues) expressed in Escherichia coli BL21 codon plus cells using Histone ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Avera Institute For Human Genetics

Curated by ChEMBL
LigandPNGBDBM50511799(CHEMBL4575499)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human GST-tagged p300 HAT domain (1195 to 1673 residues) expressed in Escherichia coli BL21 codon plus cells using Histone ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Avera Institute For Human Genetics

Curated by ChEMBL
LigandPNGBDBM50511798(CHEMBL4470175)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human GST-tagged p300 HAT domain (1195 to 1673 residues) expressed in Escherichia coli BL21 codon plus cells using Histone ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Avera Institute For Human Genetics

Curated by ChEMBL
LigandPNGBDBM50511793(CHEMBL4443949)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human GST-tagged p300 HAT domain (1195 to 1673 residues) expressed in Escherichia coli BL21 codon plus cells using Histone ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Avera Institute For Human Genetics

Curated by ChEMBL
LigandPNGBDBM50511792(CHEMBL4438839)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human GST-tagged p300 HAT domain (1195 to 1673 residues) expressed in Escherichia coli BL21 codon plus cells using Histone ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Avera Institute For Human Genetics

Curated by ChEMBL
LigandPNGBDBM50511790(CHEMBL4579124)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human GST-tagged p300 HAT domain (1195 to 1673 residues) expressed in Escherichia coli BL21 codon plus cells using Histone ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Avera Institute For Human Genetics

Curated by ChEMBL
LigandPNGBDBM50511789(CHEMBL4474132)
Affinity DataIC50: 1.35E+4nMAssay Description:Inhibition of His6-tagged p300 HAT domain (unknown origin) assessed as disruption of p300 and Histone H4 (1-21) peptide interaction incubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT6A [507-778](Human)
Avera Institute For Human Genetics

Curated by ChEMBL
LigandPNGBDBM50511789(CHEMBL4474132)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant human GST-tagged Myst3 expressed in Escherichia coli BL21 codon plus cells using Histone H3 peptide (1 to 21) and [3H]acety...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT2B(Human)
Avera Institute For Human Genetics

Curated by ChEMBL
LigandPNGBDBM50511789(CHEMBL4474132)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant human GST-tagged PCAF expressed in Escherichia coli BL21 codon plus cells using Histone H3 peptide (1 to 21) and [3H]acetyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed