Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50007994
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50514710(CHEMBL4555677)
Affinity DataIC50: 62nMAssay Description:Inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction in radiolabel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50514715(CHEMBL4543218)
Affinity DataIC50: 92nMAssay Description:Inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction in radiolabel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50514717(CHEMBL4462702)
Affinity DataIC50: 120nMAssay Description:Inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction in radiolabel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50216786(N-(7-Amino-heptyl)-guanidine | N-guanyl-1,7-diamin...)
Affinity DataIC50: 140nMAssay Description:Inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction in radiolabel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50514706(CHEMBL4442298)
Affinity DataIC50: 430nMAssay Description:Inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction in radiolabel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50216786(N-(7-Amino-heptyl)-guanidine | N-guanyl-1,7-diamin...)
Affinity DataIC50: 500nMAssay Description:Competitive inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50514699(CHEMBL4447948)
Affinity DataIC50: 840nMAssay Description:Inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction in radiolabel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50514698(CHEMBL4470208)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction in radiolabel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50514714(CHEMBL4572958)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction in radiolabel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50514710(CHEMBL4555677)
Affinity DataIC50: 6.90E+3nMAssay Description:Competitive inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50514707(CHEMBL4439037)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction in radiolabel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50514713(CHEMBL4559429)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction in radiolabel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50514699(CHEMBL4447948)
Affinity DataIC50: 3.80E+4nMAssay Description:Competitive inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50514702(CHEMBL4572059)
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction in radiolabel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50514710(CHEMBL4555677)
Affinity DataIC50: 5.60E+4nMAssay Description:Competitive inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50514712(CHEMBL4445752)
Affinity DataIC50: 9.90E+4nMAssay Description:Inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction in radiolabel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50514709(CHEMBL4472269)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction in radiolabel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50514708(CHEMBL4520351)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction in radiolabel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50514711(CHEMBL4457831)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction in radiolabel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50514705(CHEMBL4437949)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction in radiolabel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50514704(CHEMBL4435260)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction in radiolabel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50514703(CHEMBL4517458)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction in radiolabel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50514701(CHEMBL4456055)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction in radiolabel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50514716(CHEMBL4437126)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction in radiolabel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50514700(CHEMBL4553169)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction in radiolabel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed