Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 8050
TargetGag-Pol polyprotein(HIV-1)
Mcgill University

LigandPNGBDBM231619(GSK5750)
Affinity DataKd:  387nMpH: 7.8Assay Description:In this case, 1 μM HIV-1 RT was added to 50 mM Tris-HCl (pH 7.8), 50 mM NaCl, 6 mM MgCl2, and varying concentrations of GSK5750 to form enzyme-i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2017
Entry Details Article
PubMed
TargetGag-Pol polyprotein(HIV-1)
Mcgill University

LigandPNGBDBM231619(GSK5750)
Affinity DataIC50: 330nMpH: 7.8 T: 2°CAssay Description:To compare activity and inhibition of E. coli RNase H with HIV-1 RNase H, theconcentration of the E. coli was adjusted to the efficiency of 500 nM HI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2017
Entry Details Article
PubMed
TargetGag-Pol polyprotein(HIV-1)
Mcgill University

LigandPNGBDBM33411(hydroxytropolone, 3 | β-Thujaplicinol)
Affinity DataIC50: 3.80E+3nMpH: 7.8 T: 2°CAssay Description:To compare activity and inhibition of E. coli RNase H with HIV-1 RNase H, theconcentration of the E. coli was adjusted to the efficiency of 500 nM HI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)