Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 3327
TargetATP-dependent RNA helicase RhlE(Vibrio fischeri (strain ATCC 700601 / ES114))
Duke University Medical Center

LigandPNGBDBM13307(1-Methyl-1H-imidazole-4-sulfonic Acid Benzyl-{2-[(...)
Affinity DataIC50: 0.5nMpH: 7.5 T: 2°CAssay Description:Assays for PfPFT activity were performed with a PFT-specific scintillation assay (SPA) kit (Amersham Biosciences, Piscataway, NJ). An amount of 1 uM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2009
Entry Details Article
PubMed
TargetATP-dependent RNA helicase RhlE(Vibrio fischeri (strain ATCC 700601 / ES114))
Duke University Medical Center

LigandPNGBDBM31423(ethylenediamine scaffold, 4)
Affinity DataIC50: 1.20nMpH: 7.5 T: 2°CAssay Description:Assays for PfPFT activity were performed with a PFT-specific scintillation assay (SPA) kit (Amersham Biosciences, Piscataway, NJ). An amount of 1 uM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2009
Entry Details Article
PubMed
TargetATP-dependent RNA helicase RhlE(Vibrio fischeri (strain ATCC 700601 / ES114))
Duke University Medical Center

LigandPNGBDBM31424(ethylenediamine scaffold, 5)
Affinity DataIC50: 3nMpH: 7.5 T: 2°CAssay Description:Assays for PfPFT activity were performed with a PFT-specific scintillation assay (SPA) kit (Amersham Biosciences, Piscataway, NJ). An amount of 1 uM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2009
Entry Details Article
PubMed
TargetATP-dependent RNA helicase RhlE(Vibrio fischeri (strain ATCC 700601 / ES114))
Duke University Medical Center

LigandPNGBDBM31425(ethylenediamine scaffold, 7)
Affinity DataIC50: 5nMpH: 7.5 T: 2°CAssay Description:Assays for PfPFT activity were performed with a PFT-specific scintillation assay (SPA) kit (Amersham Biosciences, Piscataway, NJ). An amount of 1 uM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2009
Entry Details Article
PubMed
LigandPNGBDBM13307(1-Methyl-1H-imidazole-4-sulfonic Acid Benzyl-{2-[(...)
Affinity DataIC50: 56nMpH: 7.7 T: 2°CAssay Description:In vitro inhibition assay of human PFT was done by measuring the incorporation of [3H] FPP (Amersham Biosciences, Piscataway, NJ) into wild type H-Ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetATP-dependent RNA helicase RhlE(Vibrio fischeri (strain ATCC 700601 / ES114))
Duke University Medical Center

LigandPNGBDBM31426(ethylenediamine scaffold, 10)
Affinity DataIC50: 70nMpH: 7.5 T: 2°CAssay Description:Assays for PfPFT activity were performed with a PFT-specific scintillation assay (SPA) kit (Amersham Biosciences, Piscataway, NJ). An amount of 1 uM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2009
Entry Details Article
PubMed
LigandPNGBDBM31425(ethylenediamine scaffold, 7)
Affinity DataIC50: 160nMpH: 7.7 T: 2°CAssay Description:In vitro inhibition assay of human PFT was done by measuring the incorporation of [3H] FPP (Amersham Biosciences, Piscataway, NJ) into wild type H-Ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM31426(ethylenediamine scaffold, 10)
Affinity DataIC50: 800nMpH: 7.7 T: 2°CAssay Description:In vitro inhibition assay of human PFT was done by measuring the incorporation of [3H] FPP (Amersham Biosciences, Piscataway, NJ) into wild type H-Ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2009
Entry Details Article
PubMed
LigandPNGBDBM31423(ethylenediamine scaffold, 4)
Affinity DataIC50: 3.70E+3nMpH: 7.7 T: 2°CAssay Description:In vitro inhibition assay of human PFT was done by measuring the incorporation of [3H] FPP (Amersham Biosciences, Piscataway, NJ) into wild type H-Ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM31424(ethylenediamine scaffold, 5)
Affinity DataIC50: 4.05E+3nMpH: 7.7 T: 2°CAssay Description:In vitro inhibition assay of human PFT was done by measuring the incorporation of [3H] FPP (Amersham Biosciences, Piscataway, NJ) into wild type H-Ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)