Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 2857
TargetAdenosine receptor A1(Human)
Monash University

LigandPNGBDBM25400(cid_657378 | CPA | CHEMBL68738 | (2R,3R,4S,5R)-2-[...)
Affinity DataKi:  9nM ΔG°:  -45.5kJ/molepH: 7.4 T: 2°CAssay Description:The displacement of [3H]DPCPX binding from the A1AR was determined using DDT1 MF-2 cell membranes. Nonspecific binding was determined in parallel ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Monash University

LigandPNGBDBM25392(Isoproterenol,(+) | CHEMBL434 | 4-[1-hydroxy-2-(pr...)
Affinity DataKi:  136nM ΔG°:  -38.8kJ/molepH: 7.4 T: 2°CAssay Description:The displacement of [125I]-(-)iodopindolol binding from the beta2AR was determined using DDT1 MF-2 cell membranes. Nonspecific binding was determined...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Monash University

LigandPNGBDBM25398(N-[5-(2-{[6-({9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hy...)
Affinity DataKi:  311nM ΔG°:  -36.8kJ/molepH: 7.4 T: 2°CAssay Description:The displacement of [125I]-(-)iodopindolol binding from the beta2AR was determined using DDT1 MF-2 cell membranes. Nonspecific binding was determined...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Monash University

LigandPNGBDBM25398(N-[5-(2-{[6-({9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hy...)
Affinity DataKi:  436nM ΔG°:  -35.9kJ/molepH: 7.4 T: 2°CAssay Description:The displacement of [3H]DPCPX binding from the A1AR was determined using DDT1 MF-2 cell membranes. Nonspecific binding was determined in parallel ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Monash University

LigandPNGBDBM25396(N-[5-(2-{[4-({9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hy...)
Affinity DataKi:  863nM ΔG°:  -34.3kJ/molepH: 7.4 T: 2°CAssay Description:The displacement of [125I]-(-)iodopindolol binding from the beta2AR was determined using DDT1 MF-2 cell membranes. Nonspecific binding was determined...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Monash University

LigandPNGBDBM25397((2R,3R,4S,5R)-2-{6-[(4-{[2-(3-amino-4-hydroxypheny...)
Affinity DataKi:  1.01E+3nM ΔG°:  -33.9kJ/molepH: 7.4 T: 2°CAssay Description:The displacement of [3H]DPCPX binding from the A1AR was determined using DDT1 MF-2 cell membranes. Nonspecific binding was determined in parallel ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Monash University

LigandPNGBDBM25399(N-[5-(1-{9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxy...)
Affinity DataKi:  1.91E+3nM ΔG°:  -32.3kJ/molepH: 7.4 T: 2°CAssay Description:The displacement of [3H]DPCPX binding from the A1AR was determined using DDT1 MF-2 cell membranes. Nonspecific binding was determined in parallel ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Monash University

LigandPNGBDBM25396(N-[5-(2-{[4-({9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hy...)
Affinity DataKi:  1.91E+3nM ΔG°:  -32.3kJ/molepH: 7.4 T: 2°CAssay Description:The displacement of [3H]DPCPX binding from the A1AR was determined using DDT1 MF-2 cell membranes. Nonspecific binding was determined in parallel ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Monash University

LigandPNGBDBM25394(N-[5-(2-{[2-({9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hy...)
Affinity DataKi:  1.98E+3nM ΔG°:  -32.2kJ/molepH: 7.4 T: 2°CAssay Description:The displacement of [3H]DPCPX binding from the A1AR was determined using DDT1 MF-2 cell membranes. Nonspecific binding was determined in parallel ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Monash University

LigandPNGBDBM25399(N-[5-(1-{9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxy...)
Affinity DataKi:  2.30E+3nM ΔG°:  -31.9kJ/molepH: 7.4 T: 2°CAssay Description:The displacement of [125I]-(-)iodopindolol binding from the beta2AR was determined using DDT1 MF-2 cell membranes. Nonspecific binding was determined...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Monash University

LigandPNGBDBM25395((2R,3R,4S,5R)-2-{6-[(2-{[2-(3-amino-4-hydroxypheny...)
Affinity DataKi:  2.75E+3nM ΔG°:  -31.4kJ/molepH: 7.4 T: 2°CAssay Description:The displacement of [3H]DPCPX binding from the A1AR was determined using DDT1 MF-2 cell membranes. Nonspecific binding was determined in parallel ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Monash University

LigandPNGBDBM25397((2R,3R,4S,5R)-2-{6-[(4-{[2-(3-amino-4-hydroxypheny...)
Affinity DataKi:  4.31E+3nM ΔG°:  -30.3kJ/molepH: 7.4 T: 2°CAssay Description:The displacement of [125I]-(-)iodopindolol binding from the beta2AR was determined using DDT1 MF-2 cell membranes. Nonspecific binding was determined...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Monash University

LigandPNGBDBM25394(N-[5-(2-{[2-({9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hy...)
Affinity DataKi: >1.00E+4nM ΔG°: >-28.3kJ/molepH: 7.4 T: 2°CAssay Description:The displacement of [125I]-(-)iodopindolol binding from the beta2AR was determined using DDT1 MF-2 cell membranes. Nonspecific binding was determined...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Monash University

LigandPNGBDBM25395((2R,3R,4S,5R)-2-{6-[(2-{[2-(3-amino-4-hydroxypheny...)
Affinity DataKi: >1.00E+4nM ΔG°: >-28.3kJ/molepH: 7.4 T: 2°CAssay Description:The displacement of [125I]-(-)iodopindolol binding from the beta2AR was determined using DDT1 MF-2 cell membranes. Nonspecific binding was determined...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed