Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 2793
LigandPNGBDBM24705(5-bromo-4-N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-N-[(...)
Affinity DataIC50: 6nMpH: 7.4 T: 2°CAssay Description:TrkA kinase activity was determined by measuring the kinase ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed
LigandPNGBDBM24706((2R)-2-({5-chloro-4-[(5-cyclopropyl-1H-pyrazol-3-y...)
Affinity DataIC50: 10nMpH: 7.4 T: 2°CAssay Description:TrkA kinase activity was determined by measuring the kinase ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed
LigandPNGBDBM24707((3S)-3-({5-chloro-4-[(5-cyclopropyl-1H-pyrazol-3-y...)
Affinity DataIC50: 13nMpH: 7.4 T: 2°CAssay Description:TrkA kinase activity was determined by measuring the kinase ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed
LigandPNGBDBM24708((3S)-3-({5-chloro-4-[(5-cyclopropyl-1H-pyrazol-3-y...)
Affinity DataIC50: 15nMpH: 7.4 T: 2°CAssay Description:TrkA kinase activity was determined by measuring the kinase ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed
LigandPNGBDBM24699(5-bromo-4-N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-N-[(...)
Affinity DataIC50: 100nMpH: 7.4 T: 2°CAssay Description:TrkA kinase activity was determined by measuring the kinase ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed
LigandPNGBDBM24701(5-bromo-4-N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-N-[(...)
Affinity DataIC50: 100nMpH: 7.4 T: 2°CAssay Description:TrkA kinase activity was determined by measuring the kinase ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed
LigandPNGBDBM24698(5-bromo-4-N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-N-[(...)
Affinity DataIC50: 120nMpH: 7.4 T: 2°CAssay Description:TrkA kinase activity was determined by measuring the kinase ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed
LigandPNGBDBM24704((2R)-2-({5-bromo-4-[(5-cyclopropyl-1H-pyrazol-3-yl...)
Affinity DataIC50: 120nMpH: 7.4 T: 2°CAssay Description:TrkA kinase activity was determined by measuring the kinase ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed
LigandPNGBDBM24694(5-bromo-4-N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-N-[(...)
Affinity DataIC50: 270nMpH: 7.4 T: 2°CAssay Description:TrkA kinase activity was determined by measuring the kinase ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed
LigandPNGBDBM24700(5-bromo-2-N-[(4-chlorophenyl)methyl]-4-N-(5-cyclop...)
Affinity DataIC50: 360nMpH: 7.4 T: 2°CAssay Description:TrkA kinase activity was determined by measuring the kinase ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed
TargetBDNF/NT-3 growth factors receptor(Human)
Astrazeneca

LigandPNGBDBM14824(JMC514672 Compound 30 | 4-({5-bromo-4-[(4-methoxyp...)
Affinity DataIC50: 646nMpH: 7.4 T: 2°CAssay Description:TrkB kinase activity was measured against its ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substrate using homog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed
LigandPNGBDBM24702(5-bromo-4-N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-N-[(...)
Affinity DataIC50: 650nMpH: 7.4 T: 2°CAssay Description:TrkA kinase activity was determined by measuring the kinase ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed
LigandPNGBDBM24696(5-bromo-4-N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-N-[(...)
Affinity DataIC50: 720nMpH: 7.4 T: 2°CAssay Description:TrkA kinase activity was determined by measuring the kinase ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed
LigandPNGBDBM24695(2-N-benzyl-5-bromo-4-N-(5-cyclopropyl-1H-pyrazol-3...)
Affinity DataIC50: 750nMpH: 7.4 T: 2°CAssay Description:TrkA kinase activity was determined by measuring the kinase ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed
TargetBDNF/NT-3 growth factors receptor(Human)
Astrazeneca

LigandPNGBDBM24694(5-bromo-4-N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-N-[(...)
Affinity DataIC50: 1.10E+3nMpH: 7.4 T: 2°CAssay Description:TrkB kinase activity was measured against its ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substrate using homog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed
LigandPNGBDBM24697(5-bromo-2-N-[(2-chlorophenyl)methyl]-4-N-(5-cyclop...)
Affinity DataIC50: 1.17E+3nMpH: 7.4 T: 2°CAssay Description:TrkA kinase activity was determined by measuring the kinase ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed
LigandPNGBDBM24703((2S)-2-({5-bromo-4-[(5-cyclopropyl-1H-pyrazol-3-yl...)
Affinity DataIC50: 1.90E+3nMpH: 7.4 T: 2°CAssay Description:TrkA kinase activity was determined by measuring the kinase ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed