Compile Data Set for Download or QSAR
Report error Found 59 Enz. Inhib. hit(s) with Target = 'Lactoperoxidase'
TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM707363(US20240408072, Compound NE-2-6)
Affinity DataIC50: 13nMAssay Description:The screening of compounds for MPO inhibition activity was conducted in three stages. The inhibitory activity of each compound against MPO was assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM707365(US20240408072, Compound NE-2-8)
Affinity DataIC50: 16nMAssay Description:The screening of compounds for MPO inhibition activity was conducted in three stages. The inhibitory activity of each compound against MPO was assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM707364(US20240408072, Compound NE-2-7)
Affinity DataIC50: 20nMAssay Description:The screening of compounds for MPO inhibition activity was conducted in three stages. The inhibitory activity of each compound against MPO was assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetLactoperoxidase(Bovine)
University of Otago Christchurch

LigandPNGBDBM217355(4-benzyl-2-hydroxybenzenecarbohydroxamic acid (HX2...)
Affinity DataIC50: 40nMAssay Description:The halogenation activities of LPO (EC 1.11.1.7) and TPO (EC 1.11.1.8) were determined using a modified method of that described previously [Ferrari ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2017
Entry Details Article
PubMed
TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM50133597(CHEBI:8502 | Propacil | Propylthiouracil | Prothyr...)
Affinity DataIC50: 119nMAssay Description:The screening of compounds for MPO inhibition activity was conducted in three stages. The inhibitory activity of each compound against MPO was assess...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM707366(US20240408072, Compound NE-2-9)
Affinity DataIC50: 130nMAssay Description:The screening of compounds for MPO inhibition activity was conducted in three stages. The inhibitory activity of each compound against MPO was assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetLactoperoxidase(Bovine)
University of Otago Christchurch

LigandPNGBDBM50015089(Salicylic hydroxamic acid | SALICYLHYDROXAMIC ACID...)
Affinity DataIC50: 400nMAssay Description:The halogenation activities of LPO (EC 1.11.1.7) and TPO (EC 1.11.1.8) were determined using a modified method of that described previously [Ferrari ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM50241361(CHEMBL1515 | METHIMAZOLE | US9138393, Methimazole ...)
Affinity DataIC50: 510nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM50638126(CHEMBL5517779)
Affinity DataIC50: 590nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetLactoperoxidase(Bovine)
University of Otago Christchurch

LigandPNGBDBM50238831(CHEMBL251689)
Affinity DataIC50: 800nMAssay Description:Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetLactoperoxidase(Bovine)
University of Otago Christchurch

LigandPNGBDBM81461(NSC_3637 | CAS_86-54-4 | Hydralazine | Hydralazine...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM50239994(CHEBI:82346 | Methylthiouracil)
Affinity DataIC50: 1.49E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetLactoperoxidase(Bovine)
University of Otago Christchurch

LigandPNGBDBM217356(2-(benzylamino)-6-oxo-3H-pyrimidine-5-carbohydroxa...)
Affinity DataIC50: 2.00E+3nMAssay Description:The halogenation activities of LPO (EC 1.11.1.7) and TPO (EC 1.11.1.8) were determined using a modified method of that described previously [Ferrari ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2017
Entry Details Article
PubMed
TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM50638128(CHEMBL5555319)
Affinity DataIC50: 2.20E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetLactoperoxidase(Bovine)
University of Otago Christchurch

LigandPNGBDBM50238837(GNF-Pf-3346 | CHEMBL581893)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetLactoperoxidase(Bovine)
University of Otago Christchurch

LigandPNGBDBM50238832(CHEMBL4080413)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetLactoperoxidase(Bovine)
University of Otago Christchurch

LigandPNGBDBM50238841(CHEMBL4098162)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetLactoperoxidase(Bovine)
University of Otago Christchurch

LigandPNGBDBM50238827(CHEMBL4064328)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetLactoperoxidase(Bovine)
University of Otago Christchurch

LigandPNGBDBM48320(SMR000058471 | METOCLOPRAMIDE | METOCLOPRAMIDE HYD...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetLactoperoxidase(Bovine)
University of Otago Christchurch

LigandPNGBDBM50489048(CHEMBL2299190)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM50638130(CHEMBL5560226)
Affinity DataIC50: 5.50E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetLactoperoxidase(Bovine)
University of Otago Christchurch

LigandPNGBDBM50489044(CHEMBL2299191)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetLactoperoxidase(Bovine)
University of Otago Christchurch

LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetLactoperoxidase(Bovine)
University of Otago Christchurch

LigandPNGBDBM50489043(CHEMBL2299192)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetLactoperoxidase(Bovine)
University of Otago Christchurch

LigandPNGBDBM217354(2-(3,5-bistrifluoromethylbenzylamino)-6-oxo-1H-pyr...)
Affinity DataIC50: 6.30E+3nMAssay Description:The halogenation activities of LPO (EC 1.11.1.7) and TPO (EC 1.11.1.8) were determined using a modified method of that described previously [Ferrari ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2017
Entry Details Article
PubMed
TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM50638124(CHEMBL5557885)
Affinity DataIC50: 7.30E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM50133597(CHEBI:8502 | Propacil | Propylthiouracil | Prothyr...)
Affinity DataIC50: 7.52E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM50507390(CHEMBL4482878 | US10981879, Example 3)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human LPO assessed as reduction in H2O2 catalyzed 3,5-iodo tyrosine formation from 3-iodotyrosine and potassium iodide preincubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetLactoperoxidase(Bovine)
University of Otago Christchurch

LigandPNGBDBM50489045(CHEMBL2299193)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetLactoperoxidase(Bovine)
University of Otago Christchurch

LigandPNGBDBM50241361(CHEMBL1515 | METHIMAZOLE | US9138393, Methimazole ...)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PDB3D3D Structure (crystal)
TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM50275890(ethyl 2,3-dihydro-3-methyl-2-selenoxoimidazole-1-c...)
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of lactoperoxidase-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM50275889(carbimazole | CHEMBL508102)
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of lactoperoxidase-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM50275891(methyl 3-methyl-2-thioxo-2,3-dihydro-1H-imidazole-...)
Affinity DataIC50: 1.07E+4nMAssay Description:Inhibition of lactoperoxidase-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM50241361(CHEMBL1515 | METHIMAZOLE | US9138393, Methimazole ...)
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of lactoperoxidase-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLactoperoxidase(Bovine)
University of Otago Christchurch

LigandPNGBDBM50489042(CHEMBL2295876)
Affinity DataIC50: 1.39E+4nMAssay Description:Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetLactoperoxidase(Bovine)
University of Otago Christchurch

LigandPNGBDBM50489049(CHEMBL2299195)
Affinity DataIC50: 1.43E+4nMAssay Description:Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetLactoperoxidase(Bovine)
University of Otago Christchurch

LigandPNGBDBM50489046(CHEMBL2299198)
Affinity DataIC50: 1.74E+4nMAssay Description:Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetLactoperoxidase(Bovine)
University of Otago Christchurch

LigandPNGBDBM50489041(CHEMBL2299196)
Affinity DataIC50: 1.78E+4nMAssay Description:Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetLactoperoxidase(Bovine)
University of Otago Christchurch

LigandPNGBDBM7458(Naringenin, 18 | 5,7-dihydroxy-2-(4-hydroxyphenyl)...)
Affinity DataIC50: 1.78E+4nMAssay Description:Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM50275895(methyl 3-ethyl-2-thioxo-2,3-dihydro-1H-imidazole-1...)
Affinity DataIC50: 1.96E+4nMAssay Description:Inhibition of lactoperoxidase-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM50275892(methyl 3-methyl-2-selenoxo-2,3-dihydro-1H-imidazol...)
Affinity DataIC50: 1.97E+4nMAssay Description:Inhibition of lactoperoxidase-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM50275893(ethyl 3-ethyl-2-thioxo-2,3-dihydro-1H-imidazole-1-...)
Affinity DataIC50: 2.05E+4nMAssay Description:Inhibition of lactoperoxidase-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM50275894(ethyl 3-ethyl-2-selenoxo-2,3-dihydro-1H-imidazole-...)
Affinity DataIC50: 2.13E+4nMAssay Description:Inhibition of lactoperoxidase-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLactoperoxidase(Bovine)
University of Otago Christchurch

LigandPNGBDBM50489039(CHEMBL2299199)
Affinity DataIC50: 2.19E+4nMAssay Description:Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM50638125(CHEMBL5557030)
Affinity DataIC50: 2.31E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM50275944(methyl 3-ethyl-2-selenoxo-2,3-dihydro-1H-imidazole...)
Affinity DataIC50: 2.53E+4nMAssay Description:Inhibition of lactoperoxidase-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLactoperoxidase(Bovine)
University of Otago Christchurch

LigandPNGBDBM50489047(CHEMBL2299194)
Affinity DataIC50: 2.64E+4nMAssay Description:Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetLactoperoxidase(Bovine)
University of Otago Christchurch

LigandPNGBDBM50489040(CHEMBL2299197)
Affinity DataIC50: 2.65E+4nMAssay Description:Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetLactoperoxidase(Bovine)
University of Otago Christchurch

LigandPNGBDBM50489038(CHEMBL2299200)
Affinity DataIC50: 3.46E+4nMAssay Description:Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM50638127(CHEMBL5558431)
Affinity DataIC50: 3.87E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
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