Compile Data Set for Download or QSAR
Report error Found 527 Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4 [58-164]'
TargetBromodomain-containing protein 4 [58-164](Human)
Genentech

US Patent
LigandPNGBDBM50557843(CHEMBL4787589 | US20250084096, Compound 15)
Affinity DataIC50: 3.30nMAssay Description:Binding of his6-tagged BRD4_BD1 bromodomain or his6-tagged BRD4_BD2 to a biotinylated bromodomain ligand (Compound C) was monitored by time resolved ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2025
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Genentech

US Patent
LigandPNGBDBM528596(US11192900, Compound 16 | US11192900, Example S-23)
Affinity DataIC50: 6nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Genentech

US Patent
LigandPNGBDBM50557838(CHEMBL4798393 | US20250084096, Compound 10a)
Affinity DataIC50: 6.60nMAssay Description:Binding of his6-tagged BRD4_BD1 bromodomain or his6-tagged BRD4_BD2 to a biotinylated bromodomain ligand (Compound C) was monitored by time resolved ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2025
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Genentech

US Patent
LigandPNGBDBM50557841(CHEMBL4751308 | US20250084096, Compound 5a)
Affinity DataIC50: 7.20nMAssay Description:Binding of his6-tagged BRD4_BD1 bromodomain or his6-tagged BRD4_BD2 to a biotinylated bromodomain ligand (Compound C) was monitored by time resolved ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2025
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Genentech

US Patent
LigandPNGBDBM528648(US11192900, Compound 616 | US11192900, Compound 70...)
Affinity DataIC50: 11nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Genentech

US Patent
LigandPNGBDBM50557842(CHEMBL4745517 | US20250084096, Compound 12a)
Affinity DataIC50: 11.3nMAssay Description:Binding of his6-tagged BRD4_BD1 bromodomain or his6-tagged BRD4_BD2 to a biotinylated bromodomain ligand (Compound C) was monitored by time resolved ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2025
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Genentech

US Patent
LigandPNGBDBM726827(tert-butyl (S)-2-(4-(4-(4- aminobut-1-yn-1-yl)phen...)
Affinity DataIC50: 13nMAssay Description:Binding of his6-tagged BRD4_BD1 bromodomain or his6-tagged BRD4_BD2 to a biotinylated bromodomain ligand (Compound C) was monitored by time resolved ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/17/2025
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Genentech

US Patent
LigandPNGBDBM50557840(CHEMBL4798822 | US20250084096, Compound 11a)
Affinity DataIC50: 14.1nMAssay Description:Binding of his6-tagged BRD4_BD1 bromodomain or his6-tagged BRD4_BD2 to a biotinylated bromodomain ligand (Compound C) was monitored by time resolved ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2025
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Genentech

US Patent
LigandPNGBDBM726724(tert-butyl (S)-2-(2,3,9- trimethyl-4-(4-(3- (methy...)
Affinity DataIC50: 14.4nMAssay Description:Binding of his6-tagged BRD4_BD1 bromodomain or his6-tagged BRD4_BD2 to a biotinylated bromodomain ligand (Compound C) was monitored by time resolved ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/17/2025
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Genentech

US Patent
LigandPNGBDBM726819(tert-butyl (S)-2-(4-(4-(3- (dimethylamino)prop-1-y...)
Affinity DataIC50: 14.5nMAssay Description:Binding of his6-tagged BRD4_BD1 bromodomain or his6-tagged BRD4_BD2 to a biotinylated bromodomain ligand (Compound C) was monitored by time resolved ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/17/2025
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Genentech

US Patent
LigandPNGBDBM726722(tert-butyl (S)-2-(4-(4-(3- aminoprop-1-yn-1-yl)phe...)
Affinity DataIC50: 15.5nMAssay Description:Binding of his6-tagged BRD4_BD1 bromodomain or his6-tagged BRD4_BD2 to a biotinylated bromodomain ligand (Compound C) was monitored by time resolved ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/17/2025
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Genentech

US Patent
LigandPNGBDBM50557839(CHEMBL4762204 | US20250084096, Compound 7a)
Affinity DataIC50: 17.8nMAssay Description:Binding of his6-tagged BRD4_BD1 bromodomain or his6-tagged BRD4_BD2 to a biotinylated bromodomain ligand (Compound C) was monitored by time resolved ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2025
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Genentech

US Patent
LigandPNGBDBM726973(tert-butyl (S)-2-(2,3,9- trimethyl-4-(4-(prop-1-yn...)
Affinity DataIC50: 18.8nMAssay Description:Binding of his6-tagged BRD4_BD1 bromodomain or his6-tagged BRD4_BD2 to a biotinylated bromodomain ligand (Compound C) was monitored by time resolved ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/17/2025
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Genentech

US Patent
LigandPNGBDBM528647(US11192900, Compound 661 | US11192900, Example S-7...)
Affinity DataIC50: 20nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Genentech

US Patent
LigandPNGBDBM726967(tert-butyl (S)-2-(4-(4-(3- (hydroxyamino)prop-1-yn...)
Affinity DataIC50: 21.1nMAssay Description:Binding of his6-tagged BRD4_BD1 bromodomain or his6-tagged BRD4_BD2 to a biotinylated bromodomain ligand (Compound C) was monitored by time resolved ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/17/2025
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Genentech

US Patent
LigandPNGBDBM528646(US11192900, Compound 406 | US11192900, Example S-7...)
Affinity DataIC50: 22nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Genentech

US Patent
LigandPNGBDBM726968(tert-butyl (S)-2-(4-(4-(3- aminopropyl)phenyl)-2,3...)
Affinity DataIC50: 23.3nMAssay Description:Binding of his6-tagged BRD4_BD1 bromodomain or his6-tagged BRD4_BD2 to a biotinylated bromodomain ligand (Compound C) was monitored by time resolved ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/17/2025
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Genentech

US Patent
LigandPNGBDBM726972(tert-butyl (S)-2-(4-(4-(but-1-yn- 1-yl)phenyl)-2,3...)
Affinity DataIC50: 23.4nMAssay Description:Binding of his6-tagged BRD4_BD1 bromodomain or his6-tagged BRD4_BD2 to a biotinylated bromodomain ligand (Compound C) was monitored by time resolved ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/17/2025
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Genentech

US Patent
LigandPNGBDBM528580(US11192900, Compound 3 | US11192900, Example S-10)
Affinity DataIC50: 24nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Genentech

US Patent
LigandPNGBDBM528580(US11192900, Compound 3 | US11192900, Example S-10)
Affinity DataIC50: 24nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Genentech

US Patent
LigandPNGBDBM726829(tert-butyl (S,E)-2-(4-(4-(3- aminoprop-1-en-1-yl)p...)
Affinity DataIC50: 25.6nMAssay Description:Binding of his6-tagged BRD4_BD1 bromodomain or his6-tagged BRD4_BD2 to a biotinylated bromodomain ligand (Compound C) was monitored by time resolved ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/17/2025
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Genentech

US Patent
LigandPNGBDBM50365262(CHEMBL1957266 | (S)-JQ1 (1) | US9320741, (S)-JQ1 |...)
Affinity DataIC50: 28.8nMAssay Description:Binding of his6-tagged BRD4_BD1 bromodomain or his6-tagged BRD4_BD2 to a biotinylated bromodomain ligand (Compound C) was monitored by time resolved ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2025
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Genentech

US Patent
LigandPNGBDBM528612(US11192900, Compound 29 | US11192900, Example S-36)
Affinity DataIC50: 30nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Genentech

US Patent
LigandPNGBDBM528582(US11192900, Compound 2 | US11192900, Example S-9)
Affinity DataIC50: 52nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Genentech

US Patent
LigandPNGBDBM580188(US11498926, Example 1A)
Affinity DataIC50: 100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2023
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Genentech

US Patent
LigandPNGBDBM318457(7-(3,5-Dimethylisoxazol-4-yl)-1-methyl-4-phenyl-4,...)
Affinity DataIC50: 100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2023
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Genentech

US Patent
LigandPNGBDBM318458(7-(3,5-Dimethylisoxazol-4-yl)-5-methyl-4-phenyl-4,...)
Affinity DataIC50: 100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2023
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Genentech

US Patent
LigandPNGBDBM318459(4-[7-(3,5-Dimethylisoxazol-4-yl)-2-oxo-1,2,4,5-tet...)
Affinity DataIC50: 100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2023
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Genentech

US Patent
LigandPNGBDBM318460(7-(3,5-Dimethylisoxazol-4-yl)-4-pyridin-3-yl-4,5-d...)
Affinity DataIC50: 100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2023
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Genentech

US Patent
LigandPNGBDBM318461(7-(3,5-Dimethylisoxazol-4-yl)-4-(3-methoxyphenyl)-...)
Affinity DataIC50: 100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2023
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Genentech

US Patent
LigandPNGBDBM318462(7-(3,5-Dimethylisoxazol-4-yl)-4-(2-methoxyphenyl)-...)
Affinity DataIC50: 100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2023
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Genentech

US Patent
LigandPNGBDBM318463(7-(3,5-Dimethylisoxazol-4-yl)-4-(2,4-difluoropheny...)
Affinity DataIC50: 100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2023
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Genentech

US Patent
LigandPNGBDBM318464(7-(3,5-Dimethylisoxazol-4-yl)-2-methyl-4-phenyl-4,...)
Affinity DataIC50: 100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2023
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Genentech

US Patent
LigandPNGBDBM318468(7-(3,5-Dimethylisoxazol-4-yl)-4-pyridin-2-yl-4,5-d...)
Affinity DataIC50: 100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2023
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Genentech

US Patent
LigandPNGBDBM318468(7-(3,5-Dimethylisoxazol-4-yl)-4-pyridin-2-yl-4,5-d...)
Affinity DataIC50: 100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2023
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Genentech

US Patent
LigandPNGBDBM318471(4-Cyclohexyl-7-(3,5-dimethylisoxazol-4-yl)-4,5-dih...)
Affinity DataIC50: 100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2023
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Genentech

US Patent
LigandPNGBDBM318474(7-(3,5-Dimethylisoxazol-4-yl)-4-(1,3-thiazol-2-yl)...)
Affinity DataIC50: 100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2023
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Genentech

US Patent
LigandPNGBDBM318475(2-{2-[7-(3,5-Dimethylisoxazol-4-yl)-2-oxo-1,2,4,5-...)
Affinity DataIC50: 100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2023
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Genentech

US Patent
LigandPNGBDBM318476(Ethyl 7-(3,5-dimethylisoxazol-4-yl)-2-oxo-4-phenyl...)
Affinity DataIC50: 100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2023
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Genentech

US Patent
LigandPNGBDBM318479(7-(3,5-Dimethylisoxazol-4-yl)-N-isopropyl-4-phenyl...)
Affinity DataIC50: 100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2023
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Genentech

US Patent
LigandPNGBDBM318480(7-(3,5-Dimethylisoxazol-4-yl)-N-methyl-4-phenyl-4,...)
Affinity DataIC50: 100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2023
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Genentech

US Patent
LigandPNGBDBM318481(7-(3,5-Dimethylisoxazol-4-yl)-N-ethyl-4-phenyl-4,5...)
Affinity DataIC50: 100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2023
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Genentech

US Patent
LigandPNGBDBM318482(7-(3,5-Dimethylisoxazol-4-yl)-N,N-dimethyl-4-pheny...)
Affinity DataIC50: 100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2023
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Genentech

US Patent
LigandPNGBDBM318483(2-{[7-(3,5-Dimethylisoxazol-4-yl)-4-phenyl-4,5-dih...)
Affinity DataIC50: 100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2023
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Genentech

US Patent
LigandPNGBDBM580219(US11498926, Example 30 | US11498926, Example 31)
Affinity DataIC50: 100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2023
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Genentech

US Patent
LigandPNGBDBM580219(US11498926, Example 30 | US11498926, Example 31)
Affinity DataIC50: 100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2023
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Genentech

US Patent
LigandPNGBDBM318486(1-{[7-(3,5-Dimethylisoxazol-4-yl)-4-phenyl-4,5-dih...)
Affinity DataIC50: 100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2023
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Genentech

US Patent
LigandPNGBDBM318488(2-[[7-(3,5-Dimethylisoxazol-4-yl)-4-phenyl-4,5-dih...)
Affinity DataIC50: 100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2023
Entry Details
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TargetBromodomain-containing protein 4 [58-164](Human)
Genentech

US Patent
LigandPNGBDBM318493(7-(3,5-Dimethylisoxazol-4-yl)-4-phenyl-4,5-dihydro...)
Affinity DataIC50: 100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2023
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Genentech

US Patent
LigandPNGBDBM318495(US9624241, Example 49 | 7-(3,5-Dimethylisoxazol-4-...)
Affinity DataIC50: 100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2023
Entry Details
Go to US Patent

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