BDBM458527 7-{2-[4-(1,2-Benzoisoxazol-3-yl)piperazin-1-yl]ethyl}-6,7-dihydro-1,7-naphthyridin-8(5H)-one::US10745401, Example 1::US11466007, Example 22::US12180213, Example 1
SMILES O=C1N(CCN2CCN(CC2)c2noc3ccccc23)CCc2cccnc12
InChI Key InChIKey=KEEGXVFJVTVUHS-UHFFFAOYSA-N
Data 12 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 458527
Affinity DataKi: 4.10nMAssay Description:Present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following procedures. CHO cell membrane ...More data for this Ligand-Target Pair
Affinity DataKi: 4.40nMAssay Description:Present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following procedures. CHO cell membrane ...More data for this Ligand-Target Pair
Affinity DataKi: 21.5nMAssay Description:Binding inhibition rate for 5-HT1A receptor (%)=100−100×{(Binding amount of [3H]8-OH-DPAT in the presence of test compound)}−(Binding amount of [3H]8...More data for this Ligand-Target Pair
Affinity DataKi: 21.5nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
Affinity DataKi: 21.5nMAssay Description:Present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following procedures. CHO cell membrane ...More data for this Ligand-Target Pair
Affinity DataKi: 49nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
Affinity DataKi: 49nMAssay Description:Binding inhibition rate for 5-HT1A receptor (%)=100−100×{(Binding amount of [3H]8-OH-DPAT in the presence of test compound)}−(Binding amount of [3H]8...More data for this Ligand-Target Pair
Affinity DataKi: 49nMAssay Description:Present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following procedures. CHO cell membrane ...More data for this Ligand-Target Pair
Affinity DataKi: 2.60E+3nMAssay Description:Present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following procedures. CHO cell membrane ...More data for this Ligand-Target Pair
Affinity DataKi: 4.96E+3nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
Affinity DataKi: 4.96E+3nMAssay Description:Present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following procedures. CHO cell membrane ...More data for this Ligand-Target Pair
Affinity DataKi: 4.96E+3nMAssay Description:Binding inhibition rate for 5-HT1A receptor (%)=100−100×{(Binding amount of [3H]8-OH-DPAT in the presence of test compound)}−(Binding amount of [3H]8...More data for this Ligand-Target Pair