BDBM31426 ethylenediamine scaffold, 10

SMILES Cn1cncc1CN(CCN(CC1CCN(CC1)C(=O)OC(C)(C)C)S(=O)(=O)c1ccccc1-c1cccc(CCC(O)=O)c1)c1ccc(cc1)C#N

InChI Key InChIKey=IQLSFMXNAXIRFW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 31426   

LigandPNGBDBM31426(ethylenediamine scaffold, 10)
Affinity DataIC50: 800nMpH: 7.7 T: 2°CAssay Description:In vitro inhibition assay of human PFT was done by measuring the incorporation of [3H] FPP (Amersham Biosciences, Piscataway, NJ) into wild type H-Ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2009
Entry Details Article
PubMed
TargetATP-dependent RNA helicase RhlE(Vibrio fischeri (strain ATCC 700601 / ES114))
Duke University Medical Center

LigandPNGBDBM31426(ethylenediamine scaffold, 10)
Affinity DataIC50: 70nMpH: 7.5 T: 2°CAssay Description:Assays for PfPFT activity were performed with a PFT-specific scintillation assay (SPA) kit (Amersham Biosciences, Piscataway, NJ). An amount of 1 uM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2009
Entry Details Article
PubMed