BDBM50333465 (2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,5S,6R)-3,4-dihydroxy-6-methyl-5-((1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-enylamino)-tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)-tetrahydro-2H-pyran-2-yloxy)-6-(hydroxymethyl)-tetrahydro-2H-pyran-2,3,4-triol::(2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,5S,6R)-3,4-dihydroxy-6-methyl-5-((1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-enylamino)-tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)-tetrahydro-2H-pyran-2-yloxy)-6-(hydroxymethyl)-tetrahydro-2H-pyran-2,3,4-triol::(2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,5S,6R)-3,4-dihydroxy-6-methyl-5-((1S,4S,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-enylamino)-tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)-tetrahydro-2H-pyran-2-yloxy)-6-(hydroxymethyl)-tetrahydro-2H-pyran-2,3,4-triol::(3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,5S,6R)-3,4-dihydroxy-6-methyl-5-((1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-enylamino)-tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)-tetrahydro-2H-pyran-2-yloxy)-6-(hydroxymethyl)-tetrahydro-2H-pyran-2,3,4-triol::5-{5-[3,4-Dihydroxy-6-methyl-5-(4,5,6-trihydroxy-3-hydroxymethyl-cyclohex-2-enylamino)-tetrahydro-pyran-2-yloxy]-3,4-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy}-6-hydroxymethyl-tetrahydro-pyran-2,3,4-triol::BAY-G 5421::CHEMBL1566::Glucobay::Precose::acarbose

SMILES C[C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O[C@@H]2[C@H](O[C@@H]([C@@H]([C@H]2O)O)O[C@@H]3[C@H](O[C@H]([C@@H]([C@H]3O)O)O)CO)CO)O)O)N[C@H]4C=C([C@H]([C@@H]([C@H]4O)O)O)CO

InChI Key InChIKey=XUFXOAAUWZOOIT-UHFFFAOYSA-N

Data  3 KI  59 IC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 62 hits for monomerid = 50333465   

TargetSucrase-isomaltase, intestinal(Rat)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 3.80E+5nMAssay Description:Inhibition of rat intestinal brush border membrane isomaltaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of rat small intestinal sucrase after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Rat)
Chulalongkorn University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of rat intestinal alpha-glucosidase maltase using maltose as substrate preincubated for 10 mins prior substrate addition measured after 40...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 2.38E+3nMAssay Description:Inhibition of rat intestinal alpha-glucosidase sucrase using sucrose as substrate preincubated for 10 mins prior substrate addition measured after 40...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Rat)
Chulalongkorn University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of alpha-glucosidase activity of maltase in rat small intestinal brush border membrane fraction using maltose as substrate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of alpha-glucosidase activity of sucrase in rat small intestinal brush border membrane fraction using maltose as substrate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
University of The Punjab

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 3.83E+4nMAssay Description:Inhibition of Saccharomyces cerevisiae alpha-glucosidase using p-nitrophenyl-alpha-D-glucopyranoside as substrate preincubated for 10 mins measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of rat intestine sucrase using sucrose as substrate incubated for 10 mins prior to substrate addition measured after 40 mins by glucose ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Rat)
Chulalongkorn University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of rat intestine maltase using maltose as substrate incubated for 10 mins prior to substrate addition measured after 40 mins by glucose ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Human)
North Maharashtra University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 1.02E+5nMAssay Description:Inhibition of pure alpha-glucosidase (unknown origin) assessed as para-nitrophenol release at 420 nm ODMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPancreatic alpha-amylase(Pig)
North Maharashtra University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 3.55E+4nMAssay Description:Inhibition of pig pancreatic alpha-amylase by Bernfeld methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAlpha-glucosidase MAL62(Baker's yeast)
University of Karachi

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 7.80E+8nMAssay Description:Inhibition of yeast alpha-glucosidase using para-nitrophenyl alpha-D-glucopyranoside as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetLactase/phlorizin hydrolase(Rat)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 1.67E+5nMAssay Description:Inhibition of rat intestinal lactase using lactose as substrate by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Rat)
Chulalongkorn University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 2.55E+4nMAssay Description:Inhibition of rat intestinal maltase using maltose as substrate by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAlpha-glucosidase MAL12(Baker's yeast)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 1.09E+5nMAssay Description:Inhibition of yeast alpha-glucosidase MAL12 assessed as inhibition of p-nitrophenol release by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Rat)
Chulalongkorn University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 350nMAssay Description:Inhibition of rat intestinal brush border membrane maltaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Rat)
Chulalongkorn University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of rat small intestinal maltase after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 560nMAssay Description:Inhibition of rat intestinal brush border membrane sucraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Human)
North Maharashtra University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of human lysosomal alpha-glucosidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Human)
North Maharashtra University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of maltase in human Caco-2 cell model system after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of rat intestinal sucrase using sucrose as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Rat)
Chulalongkorn University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 180nMAssay Description:Inhibition of rat intestinal maltase using moltose as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPancreatic alpha-amylase(Pig)
North Maharashtra University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 3.55E+4nMAssay Description:Inhibition of porcine pancreatic alpha amylase using starch as substrate by Bernfeld methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Mouse)
North Maharashtra University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of liver glucosidase in Swiss mouse liver extractsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of rat intestinal sucraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 1.55E+5nMAssay Description:Inhibition of rat intestinal isomaltaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Rat)
Chulalongkorn University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of rat intestinal maltaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Rat)
Chulalongkorn University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 6.38E+3nMAssay Description:Inhibition of rat intestinal alpha-glucosidase using p-nitrophenyl- alpha-D-glucopyranoside as substrate preincubated for 5 min before addition of su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetAlpha-glucosidase MAL62(Baker's yeast)
University of Karachi

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 9.08E+5nMAssay Description:Inhibition of yeast alpha-glucosidase using p-nitrophenyl-alpha-D-glucopyranoside as substrate preincubated for 10 min before substrate addition and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetLysosomal alpha-glucosidase(Human)
North Maharashtra University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 1.70E+6nMAssay Description:Inhibition of alpha-glucosidase (unknown origin) using para-nitrophenyl-alpha-D-glucopyranoside as substrate incubated for 15 min prior to substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetLysosomal alpha-glucosidase(Rat)
Chulalongkorn University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 1.86E+4nMAssay Description:Inhibition of rat intestinal alpha-glucosidase using para-nitrophenyl-alpha-D-glucopyranoside as substrate incubated for 5 min prior to substrate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetLysosomal alpha-glucosidase(Rat)
Chulalongkorn University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 1.61E+4nMAssay Description:Inhibition of maltase in rat intestinal mucosa pre-incubated for 40 mins using maltose substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2016
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
University of The Punjab

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 2.35E+5nMAssay Description:Inhibition of Saccharomyces cerevisiae alpha-glucosidase assessed as 4-nitrophenol release from 4-nitrophenyl alpha-D-glucopyranoside preincubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 400nMAssay Description:Inhibition of rat intestinal sucrase using sucrose as substrate assessed as D-glucose release from substrate preincubated for 15 mins measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAlpha-glucosidase MAL12(Baker's yeast)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 3.83E+4nMpH: 6.8 T: 2°CAssay Description:Reaction mixture (100 µL) contained 70 µL 50 mM Na2HPO4 buffer, pH 6.8, 10 µL test compound (0.5 mM), followed by the addition of 10 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetAlpha-glucosidase MAL12(Baker's yeast)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 2.30E+5nMAssay Description:The assay was performed using isolated phenolics from maize, and inhibition was determined according to previously described method.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2014
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
University of The Punjab

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 3.83E+4nMT: 2°CAssay Description:A 100 µL assay mixture containing 70 µL phosphate buffer saline (50 mM at pH 6.8), 10 µL corresponding test compounds dissolved in methanol/DMSO (0.5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2015
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
University of The Punjab

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 3.83E+4nMpH: 6.8Assay Description:Typically, α-glucosidase activity was assayed in 50 mM phosphate buffer (pH 6.8) containing 5% v/v DMSO and PNP glycoside was used as a substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2015
Entry Details Article
PubMed
TargetAlpha-glucosidase MAL12(Baker's yeast)
Universidade Federal Do Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 8.40E+5nMAssay Description:10 µL of test samples (5 mg/mL DMSO solution) were reconstituted in 100 µL of 100 mM-phosphate buffer (pH6.8) in 96-well microplate and incubated wit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
University of The Punjab

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 3.83E+4nMpH: 6.8Assay Description:Total volume of 100 µL reaction mixture contained 70 µL 50 mM phosphate buffer pH 6.8, 10 µL test compound (0.5 mM in methanol) followed by the addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of rat intestinal sucrase using sucrose substrate incubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Rat)
Chulalongkorn University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 180nMAssay Description:Inhibition of Wistar rat intestinal maltase assessed as inhibition of D-glucose release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of Wistar rat intestinal sucrase assessed as inhibition of D-glucose release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
University of The Punjab

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 1.16E+5nMAssay Description:Inhibition of bakers yeast alpha-glucosidase using p-nitrophenyl-alpha-D-glucopyranoside as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetMaltase-glucoamylase(Human)
Universiti Teknologi Mara (Uitm)

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 9.06E+5nMAssay Description:Inhibition of alpha-glucosidase (unknown origin) using pNPG substrate incubated for 15 mins by microplate reader based methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Human)
North Maharashtra University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 4.47E+5nMAssay Description:Inhibition of alpha-glucosidase (unknown origin) pre-incubated for 20 mins before p-nitrophenyl glycoside substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2016
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 2.02E+4nMAssay Description:Inhibition of sucrase in rat intestinal mucosa pre-incubated for 40 mins using sucrose substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2016
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Rat)
Chulalongkorn University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of rat intestinal maltase using maltose as substrate assessed as D-glucose release from substrate preincubated for 15 mins measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
University of The Punjab

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 6.70E+5nMAssay Description:Inhibition of yeast alpha-glucosidase using p-NPG as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2016
Entry Details Article
PubMed
TargetAlpha-amylase 1A(Human)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 500nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrate by UV-Vis spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2016
Entry Details Article
PubMed
Displayed 1 to 50 (of 62 total ) | Next | Last >>