BDBM233141 1,2-Diphenylhydrazine::Mr-II-10

SMILES N(Nc1ccccc1)c1ccccc1

InChI Key InChIKey=YBQZXXMEJHZYMB-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 233141   

TargetPlasmepsin II(Plasmodium falciparum)
University of Karachi

LigandPNGBDBM233141(1,2-Diphenylhydrazine | Mr-II-10)
Affinity DataIC50: 1.05E+3nMpH: 5.0Assay Description:The assay was performed with plasmepsin-II/cathepsin D (1.2 nM) and substrate (malaria FRET-1; 1.0 μM) in 0.1 M sodium acetate buffer pH 5, contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2017
Entry Details Article
PubMed
TargetCathepsin D(Human)
University of Karachi

LigandPNGBDBM233141(1,2-Diphenylhydrazine | Mr-II-10)
Affinity DataIC50: 2.40E+3nMpH: 5.0Assay Description:The assay was performed with plasmepsin-II/cathepsin D (1.2 nM) and substrate (malaria FRET-1; 1.0 μM) in 0.1 M sodium acetate buffer pH 5, contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2017
Entry Details Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
University of Karachi

LigandPNGBDBM233141(1,2-Diphenylhydrazine | Mr-II-10)
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of recombinant Plasmodium falciparum Plasmepsin 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetCathepsin D(Human)
University of Karachi

LigandPNGBDBM233141(1,2-Diphenylhydrazine | Mr-II-10)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetCathepsin D(Human)
University of Karachi

LigandPNGBDBM233141(1,2-Diphenylhydrazine | Mr-II-10)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human liver cathepsin D using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
University of Karachi

LigandPNGBDBM233141(1,2-Diphenylhydrazine | Mr-II-10)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 2 using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed