BDBM50664172 Elagolix::NBI-56418

SMILES CC1=C(C(=O)N(C(=O)N1Cc2c(cccc2F)C(F)(F)F)C[C@@H](c3ccccc3)NCCCC(=O)O)c4cccc(c4F)OC

InChI Key InChIKey=HEAUOKZIVMZVQL-UHFFFAOYSA-N

Data  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50664172   

TargetGonadotropin-releasing hormone receptor(Human)
University of Milan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664172BDBM50664172(Elagolix | NBI-56418)
Affinity DataEC50:  0.600nMAssay Description:Antagonist activity at wild type HA-tagged human GnRH1 receptor expressed in HEK293T cells assessed as inhibition of GnRH peptide-stimulated IP1 accu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)