BDBM734010 US20250127913, Compound I-94

SMILES N#Cc1ccc(F)c([C@@H](C)Nc2c(Cl)c(C)nc3cc(F)c(-c4cnc(N5CCN(C(=O)COCCn6cc(CN(C)CCOCCOCCOCCNC(=O)CC[C@H](NC(=O)c7ccc(NCc8cnc9nc(N)nc(O)c9n8)cc7)C(=O)O)nn6)CC5)nc4)nc23)c1

InChI Key InChIKey=LEQMZSHFEQRYKA-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 734010   

TargetTumor necrosis factor(Human)
Lycia Therapeutics

US Patent
LigandPNGBDBM734010(US20250127913, Compound I-94)
Affinity DataIC50: 22nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetFolate receptor beta(Human)
Lycia Therapeutics

US Patent
LigandPNGBDBM734010(US20250127913, Compound I-94)
Affinity DataIC50: 9.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetFolate receptor beta(Human)
Lycia Therapeutics

US Patent
LigandPNGBDBM734010(US20250127913, Compound I-94)
Affinity DataKd:  0.0190nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent