BDBM734006 US20250127913, Compound I-98

SMILES Cc1nc2cc(F)c(-c3cnc(N4CCN(C(=O)COCCn5cc(COCCOCCOCCOCCCC(=O)CC[C@H](NC(=O)c6ccc(SCCc7cc8c(=O)[nH]c(N)nc8[nH]7)cc6)C(=O)O)nn5)CC4)nc3)nc2c(N[C@H](C)c2cc(C#N)ccc2F)c1Cl

InChI Key InChIKey=ULXKKIGEUKGYFV-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 734006   

TargetTumor necrosis factor(Human)
Lycia Therapeutics

US Patent
LigandPNGBDBM734006(US20250127913, Compound I-98)
Affinity DataIC50: 19nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetFolate receptor beta(Human)
Lycia Therapeutics

US Patent
LigandPNGBDBM734006(US20250127913, Compound I-98)
Affinity DataIC50: 133nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetFolate receptor beta(Human)
Lycia Therapeutics

US Patent
LigandPNGBDBM734006(US20250127913, Compound I-98)
Affinity DataKd:  0.172nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent