BDBM734005 US20250127913, Compound I-91

SMILES Cc1nc2cc(F)c(-c3cnc(N4CCN(C(=O)COCCn5cc(COCCOCCOCCOCCNC(=O)CC[C@H](NC(=O)[C@H]6CC[C@H](NCc7cnc8nc(N)nc(O)c8n7)CC6)C(=O)O)nn5)CC4)nc3)nc2c(N[C@H](C)c2ccccc2F)c1Cl

InChI Key InChIKey=XGXBMGWSSWJKMV-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 734005   

TargetTumor necrosis factor(Human)
Lycia Therapeutics

US Patent
LigandPNGBDBM734005(US20250127913, Compound I-91)
Affinity DataIC50: 17.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetFolate receptor beta(Human)
Lycia Therapeutics

US Patent
LigandPNGBDBM734005(US20250127913, Compound I-91)
Affinity DataIC50: 138nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetFolate receptor beta(Human)
Lycia Therapeutics

US Patent
LigandPNGBDBM734005(US20250127913, Compound I-91)
Affinity DataKd:  0.201nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent