BDBM726563 US20250084039, Compound HSN178

SMILES CN(C)CC(O)CNC(=O)c1cccc(C#Cc2c(N)ncc3ccc(Cl)cc23)c1

InChI Key InChIKey=URKDKXXBZXRMCU-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 726563   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM726563(US20250084039, Compound HSN178)
Affinity DataKd:  53nMAssay Description:Table 8: The binding of HSN286, HSN336, HSN334, HSN248 and HSN247 with several FLT3 secondary mutations (Table 8) was investigated. Interestingly, HS...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/16/2025
Entry Details
Go to US Patent

TargetDimer of Receptor-type tyrosine-protein kinase FLT3(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM726563(US20250084039, Compound HSN178)
Affinity DataKd:  450nMAssay Description:Table 8: The binding of HSN286, HSN336, HSN334, HSN248 and HSN247 with several FLT3 secondary mutations (Table 8) was investigated. Interestingly, HS...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/16/2025
Entry Details
Go to US Patent