| Assay Method Information | |
| | Binding with FLT3 Secondary Mutations |
| Description: | Table 8: The binding of HSN286, HSN336, HSN334, HSN248 and HSN247 with several FLT3 secondary mutations (Table 8) was investigated. Interestingly, HSN356 could bind to FLT3 (D835V) with a Kd of 19 nM, whereas a similar compound, HSN334, was a poor binder of FLT3 (D835V) with a Kd of 120 nM (Table 8). |
| Affinity data for this assay | |
|---|---|
| If you find an error in this entry please send us an E-mail | |