BDBM720737 3-(4-chloro-6-piperazin-1-yl-2-pyridyl)-5-(trifluoromethyl) pyrazolo[1,5-a]pyridine::US20250051363, Example 41

SMILES Cc1ccn2ncc(-c3cc(Cl)cc(N4CCNCC4)n3)c2c1

InChI Key InChIKey=GLDPBAZMLKJXKI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 720737   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Neuro3 Therapeutics

US Patent
LigandPNGBDBM720737(3-(4-chloro-6-piperazin-1-yl-2-pyridyl)-5-(trifluo...)
Affinity DataIC50: 55nMAssay Description:The ability of a compound of Formula (I) to inhibit LRRK2 kinase activity is measured using a LanthaScreen™ kinase activity assay. In general, in a L...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
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