BDBM719030 4-((2-(1H-indol-3-yl)ethyl)amino)-2-(5-fluoropyridin-3-yl)-N,N-dimethyl-5,8-dihydropyrido[3,4-d]pyrimidine-7(6H)-carboxamide::US12221439, Example 13

SMILES CN(C)C(=O)N1CCc2c(nc(-c3cncc(F)c3)nc2NCCc2c[nH]c3ccccc23)C1

InChI Key InChIKey=WGVKXFZXMMYESB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 719030   

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandPNGBDBM719030(4-((2-(1H-indol-3-yl)ethyl)amino)-2-(5-fluoropyrid...)
Affinity DataIC50: 2.00E+3nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
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