BDBM719021 2-(4-((2-(1H-indol-3-yl)ethyl)amino)-2-(5-fluoropyridin-3-yl)-5,8-dihydropyrido[3,4-d]pyrimidin-7(6H)-yl)acetonitrile::US12221439, Example 4

SMILES N#CCN1CCc2c(ncc(F)c2NCCc2c[nH]c3ccccc23)C1

InChI Key InChIKey=NSVONEQZUJNMHK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 719021   

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandPNGBDBM719021(2-(4-((2-(1H-indol-3-yl)ethyl)amino)-2-(5-fluoropy...)
Affinity DataIC50: 794nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
Go to US Patent