BDBM716254 US20250032489, Compound 160

SMILES Cc1cnc(Nc2cc(C3CCN(C(C)C)CC3)cc(N3CCC(F)(F)C3)n2)cn1

InChI Key InChIKey=UFKLFYGNKYPEHJ-UHFFFAOYSA-N

Data  4 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 716254   

TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandPNGBDBM716254(US20250032489, Compound 160)
Affinity DataKd:  9.60nMAssay Description:One hundred nanograms of glutathione S-transferase (GST)-tagged human LZK pure protein (Carna Biosciences, #09-114) was incubated with 100 ng of GST-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetProtein delta homolog 1(Human)
Department of Health And Human Services

US Patent
LigandPNGBDBM716254(US20250032489, Compound 160)
Affinity DataKd:  11nMAssay Description:One hundred nanograms of glutathione S-transferase (GST)-tagged human LZK pure protein (Carna Biosciences, #09-114) was incubated with 100 ng of GST-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandPNGBDBM716254(US20250032489, Compound 160)
Affinity DataKd:  9.60nMAssay Description:One hundred nanograms of glutathione S-transferase (GST)-tagged human LZK pure protein (Carna Biosciences, #09-114) was incubated with 100 ng of GST-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetProtein delta homolog 1(Human)
Department of Health And Human Services

US Patent
LigandPNGBDBM716254(US20250032489, Compound 160)
Affinity DataKd:  11nMAssay Description:One hundred nanograms of glutathione S-transferase (GST)-tagged human LZK pure protein (Carna Biosciences, #09-114) was incubated with 100 ng of GST-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent