BDBM707713 US20240417395, Example 7

SMILES CCCCC1=N[C@@]2(CC3C[C@H]3C2)C(=O)N1Cc1ccc(-c2ccccc2S(=O)(=O)Nc2noc(C)c2Cl)c(COCC)c1

InChI Key InChIKey=PIOHCDHXAFHBLR-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 707713   

TargetCytochrome P450 1A2(Human)
Nicoya Therapeutics (Shanghai) Co.

US Patent
LigandPNGBDBM707713(US20240417395, Example 7)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory Effects on Activities of Cytochrome P450 Isozymes (CYP1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A4) from Human Liver Microsomes. A total of si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/1/2025
Entry Details
Go to US Patent

TargetCytochrome P450 2C9(Human)
Nicoya Therapeutics (Shanghai) Co.

US Patent
LigandPNGBDBM707713(US20240417395, Example 7)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory Effects on Activities of Cytochrome P450 Isozymes (CYP1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A4) from Human Liver Microsomes. A total of si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/1/2025
Entry Details
Go to US Patent

TargetCytochrome P450 2C19(Human)
Nicoya Therapeutics (Shanghai) Co.

US Patent
LigandPNGBDBM707713(US20240417395, Example 7)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory Effects on Activities of Cytochrome P450 Isozymes (CYP1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A4) from Human Liver Microsomes. A total of si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/1/2025
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Nicoya Therapeutics (Shanghai) Co.

US Patent
LigandPNGBDBM707713(US20240417395, Example 7)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory Effects on Activities of Cytochrome P450 Isozymes (CYP1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A4) from Human Liver Microsomes. A total of si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/1/2025
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Nicoya Therapeutics (Shanghai) Co.

US Patent
LigandPNGBDBM707713(US20240417395, Example 7)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory Effects on Activities of Cytochrome P450 Isozymes (CYP1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A4) from Human Liver Microsomes. A total of si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/1/2025
Entry Details
Go to US Patent

TargetCytochrome P450 2C8(Human)
Nicoya Therapeutics (Shanghai) Co.

US Patent
LigandPNGBDBM707713(US20240417395, Example 7)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory Effects on Activities of Cytochrome P450 Isozymes (CYP1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A4) from Human Liver Microsomes. A total of si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/1/2025
Entry Details
Go to US Patent