BDBM707676 US20240417387, Example 014

SMILES NC(=O)[C@H]1CC[C@H](C(F)(F)c2cc(Cl)nc(N3CCN(S(=O)(=O)c4ccc(N5C[C@H](N)CC5=O)cc4)CC3)c2)CC1

InChI Key InChIKey=FVEPAVGNJKSQHJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 707676   

TargetUDP-2,3-diacylglucosamine hydrolase()
Hoffmann-La Roche

US Patent
LigandPNGBDBM707676(US20240417387, Example 014)
Affinity DataIC50: 2nMAssay Description:The inhibitory potency of compounds of Escherichia coli UDP-2,3-diacylglucosamine hydrolase (LpxH) was determined in an enzymatic assay. UDP-2,3-diac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/1/2025
Entry Details
Go to US Patent

TargetUDP-2,3-diacylglucosamine hydrolase()
Hoffmann-La Roche

US Patent
LigandPNGBDBM707676(US20240417387, Example 014)
Affinity DataIC50: 2nMAssay Description:The inhibitory potency of molecules to UDP-2,3-diacylglucosamine hydrolase (LpxH) was determined using the UMP/CMP-Glo™ Glycosyltransferase Assay kit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/22/2025
Entry Details
Go to US Patent