BDBM707366 US20240408072, Compound NE-2-9

SMILES COc1ccc2c(c1)c(-c1c[nH]c(NC(=O)C3CC(=O)OC3(C)C)n1)c(C)n2C

InChI Key InChIKey=DSLFLGGUUFQOKR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 707366   

TargetMyeloperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM707366(US20240408072, Compound NE-2-9)
Affinity DataIC50: 1.83E+3nMAssay Description:The screening of compounds for MPO inhibition activity was conducted in three stages. The inhibitory activity of each compound against MPO was assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM707366(US20240408072, Compound NE-2-9)
Affinity DataIC50: 130nMAssay Description:The screening of compounds for MPO inhibition activity was conducted in three stages. The inhibitory activity of each compound against MPO was assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent