BDBM707365 US20240408072, Compound NE-2-8

SMILES Cc1ccn2c(Nc3ccc4c(c3)OCO4)c(-c3ccc(O)cc3)nc2c1

InChI Key InChIKey=LIQHAYUELMDDMK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 707365   

TargetMyeloperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM707365(US20240408072, Compound NE-2-8)
Affinity DataIC50: 770nMAssay Description:The screening of compounds for MPO inhibition activity was conducted in three stages. The inhibitory activity of each compound against MPO was assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetThyroid peroxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM707365(US20240408072, Compound NE-2-8)
Affinity DataIC50: 1.05E+3nMAssay Description:The screening of compounds for MPO inhibition activity was conducted in three stages. The inhibitory activity of each compound against MPO was assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM707365(US20240408072, Compound NE-2-8)
Affinity DataIC50: 16nMAssay Description:The screening of compounds for MPO inhibition activity was conducted in three stages. The inhibitory activity of each compound against MPO was assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent