BDBM707364 US20240408072, Compound NE-2-7

SMILES COc1ccc(-c2nc3cc(C)ccn3c2Nc2ccc3c(c2)OCO3)cc1

InChI Key InChIKey=FDEJOXGXXZIAPE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 707364   

TargetMyeloperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM707364(US20240408072, Compound NE-2-7)
Affinity DataIC50: 1.50E+3nMAssay Description:The screening of compounds for MPO inhibition activity was conducted in three stages. The inhibitory activity of each compound against MPO was assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetThyroid peroxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM707364(US20240408072, Compound NE-2-7)
Affinity DataIC50: 2.25E+3nMAssay Description:The screening of compounds for MPO inhibition activity was conducted in three stages. The inhibitory activity of each compound against MPO was assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM707364(US20240408072, Compound NE-2-7)
Affinity DataIC50: 20nMAssay Description:The screening of compounds for MPO inhibition activity was conducted in three stages. The inhibitory activity of each compound against MPO was assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent