BDBM707363 US20240408072, Compound NE-2-6

SMILES Cc1ccc2nc(-c3cccnc3)c(Nc3ccc4c(c3)OCO4)n2c1

InChI Key InChIKey=VUYXOBFHLJVYNA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 707363   

TargetMyeloperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM707363(US20240408072, Compound NE-2-6)
Affinity DataIC50: 6.45E+3nMAssay Description:The screening of compounds for MPO inhibition activity was conducted in three stages. The inhibitory activity of each compound against MPO was assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetThyroid peroxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM707363(US20240408072, Compound NE-2-6)
Affinity DataIC50: 890nMAssay Description:The screening of compounds for MPO inhibition activity was conducted in three stages. The inhibitory activity of each compound against MPO was assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetLactoperoxidase(Human)
Esgelbio

US Patent
LigandPNGBDBM707363(US20240408072, Compound NE-2-6)
Affinity DataIC50: 13nMAssay Description:The screening of compounds for MPO inhibition activity was conducted in three stages. The inhibitory activity of each compound against MPO was assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent