BDBM707292 US12161646, Example 3A

SMILES [2H]C1([2H])Sc2ccccc2[C@]([2H])(N2[C@@H]3COCCN3C(=O)c3c(O)c(=O)ccn32)c2ccc(F)c(F)c21

InChI Key InChIKey=FIDLLEYNNRGVFR-DPQMAWMNSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 707292   

TargetRNA-directed RNA polymerase catalytic subunit/Polymerase basic protein 1/Polymerase basic protein 2(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Jiaxing Andicon Biotech Co.

US Patent
LigandPNGBDBM707292(US12161646, Example 3A)
Affinity DataIC50: 1.65nMAssay Description:2.5 μL of enzymatic reaction mixture (composition: 53 mM Tris hydrochloride (pH 7.8), 1 mM MgCl2, 1.25 mM dithiothreitol, 80 mM NaCl, 12.5% glycerol,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
Go to US Patent

TargetRNA-directed RNA polymerase catalytic subunit/Polymerase basic protein 1/Polymerase basic protein 2(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Jiaxing Andicon Biotech Co.

US Patent
LigandPNGBDBM707292(US12161646, Example 3A)
Affinity DataEC50:  0.600nMAssay Description:MDCK cells were seeded in a 96-well cell culture plate, and cultured till cell attachment for later use. The drug was serially 3 times diluted from 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
Go to US Patent