BDBM700682 5-((4-(Pyridin-4-ylmethoxy)but-2-yn-1-yl)amino)- 2-(2,3,5-trichlorophenyl)oxazole-4-carbonitrile::US20240336642, Compound 87

SMILES Clc1cc(Cl)c(Cl)c(c1)-c1nc(C#N)c(NCC#CCOCc2ccc(OCCN3CCOCC3)cc2)o1

InChI Key InChIKey=MACYAMHINJIALM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 700682   

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700682(US20240336642, Compound 87 | 5-((4-(Pyridin-4-ylme...)
Affinity DataIC50: 210nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
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Date in BDB:
2/10/2025
Entry Details
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