BDBM700614 2-(3,5-Dichloro-2-methylpheny1)-5-((4- hydroxybutyl)amino)oxazole-4-carbonitrile::US20240336642, Compound 19

SMILES Cc1c(Cl)cc(Cl)cc1-c1nc(C#N)c(NCCCCO)o1

InChI Key InChIKey=XXRBIVXHXZEZSW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 700614   

TargetPolyunsaturated fatty acid lipoxygenase ALOX12/ALOX15(Human)
The General Hospital

US Patent
LigandPNGBDBM700614(US20240336642, Compound 19 | 2-(3,5-Dichloro-2-met...)
Affinity DataIC50: 460nMAssay Description:Assay: Compounds are dissolved in DMSO and diluted to 10 mM concentration in DMSO immediately before IC50 analysis. To determine inhibition of the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent