BDBM696888 US20240308985, Comparator 123::US20250170100, Comparator 123

SMILES COc1ccc(F)c(c1)C(=O)N1CC2(CC(C2)c2cc(C)nn2-c2ccccc2C)C1

InChI Key InChIKey=MDWSGUXEWDYFCB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 696888   

TargetMonoglyceride lipase [2-303](Homo sapiens (Human))
Psy Therapeutics

US Patent
LigandPNGBDBM696888(US20240308985, Comparator 123 | US20250170100, Com...)
Affinity DataIC50: 1.00E+4nMAssay Description:MAGL Inhibition was measured by the following assay. Monoacylglycerol Lipase (MAGL) inhibition was measured using recombinant MAGL enzyme (aa 2-303 R...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/16/2025
Entry Details
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TargetFatty-acid amide hydrolase 1(Human)
Psy Therapeutics

US Patent
LigandPNGBDBM696888(US20240308985, Comparator 123 | US20250170100, Com...)
Affinity DataIC50: 1.00E+4nMAssay Description:MAGL inhibitor compounds were also counter-screened for FAAH inhibition potency using the following assay. Assessment of FAAH inhibition was performe...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/16/2025
Entry Details
Go to US Patent

TargetFatty-acid amide hydrolase 1(Human)
Psy Therapeutics

US Patent
LigandPNGBDBM696888(US20240308985, Comparator 123 | US20250170100, Com...)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/22/2025
Entry Details
Go to US Patent

TargetMonoglyceride lipase(Human)
Psy Therapeutics

US Patent
LigandPNGBDBM696888(US20240308985, Comparator 123 | US20250170100, Com...)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/22/2025
Entry Details
Go to US Patent