BDBM696636 US20240308985, Compound 120

SMILES Cc1cc(C2=CC3(CN(C3)C(=O)c3cc(O)ccc3F)C2)n(n1)-c1ccccc1C

InChI Key InChIKey=NLGKZYJMKADQFP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 696636   

TargetMonoglyceride lipase [2-303](Homo sapiens (Human))
Psy Therapeutics

US Patent
LigandPNGBDBM696636(US20240308985, Compound 120)
Affinity DataIC50: 325nMAssay Description:MAGL Inhibition was measured by the following assay. Monoacylglycerol Lipase (MAGL) inhibition was measured using recombinant MAGL enzyme (aa 2-303 R...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/16/2025
Entry Details
Go to US Patent

TargetFatty-acid amide hydrolase 1(Human)
Psy Therapeutics

US Patent
LigandPNGBDBM696636(US20240308985, Compound 120)
Affinity DataIC50: 1.00E+4nMAssay Description:MAGL inhibitor compounds were also counter-screened for FAAH inhibition potency using the following assay. Assessment of FAAH inhibition was performe...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/16/2025
Entry Details
Go to US Patent